Genistein, a potential phytochemical against breast cancer treatment-insight into the molecular mechanisms

M Sohel, P Biswas, M Al Amin, MA Hossain, H Sultana… - Processes, 2022 - mdpi.com
effects as synthetic drugs with fewer side effects on normal cells. Therefore, we aimed to unravel
and analyze several molecular mechanisms of genistein (GNT) … possible mechanisms of …

Cellular and molecular mechanisms of genistein in prevention and treatment of diseases: An overview

F Nazari‐Khanamiri… - Journal of Food …, 2021 - Wiley Online Library
effect of NF-κB1 upon inhibition by genistein. According to the result of this study, genistein
… key role in the inhibition of breast cancer. The findings from this in silico analysis suggested …

Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
… of preclinical pharmacological activities with mechanisms of action, … cancer cells, it stimulated
protein alterations and changed the molecular mechanism which is responsible for actions

Genistein: a potent anti-breast cancer agent

SS Bhat, SK Prasad, C Shivamallu, KS Prasad… - … Issues in Molecular …, 2021 - mdpi.com
… Such a development of genistein in chemotherapy may be a powerful tool in … The current
review focuses mainly on the molecular basis of the anti-breast cancer potential of genistein, …

Therapeutic potentials of genistein: New insights and perspectives

S Rasheed, K Rehman, M Shahid… - Journal of Food …, 2022 - Wiley Online Library
… for cancer treatment. This article highlights the protective and therapeutic benefits of genistein
… specifically elaborates on the anti-cancer potential of genistein regarding various types of …

Genistein as a regulator of signaling pathways and microRNAs in different types of cancers

Z Javed, K Khan, J Herrera-Bravo, S Naeem… - Cancer Cell …, 2021 - Springer
… in functional genomics have laid foundation of a new frontier in molecular oncology and
understanding of molecular mechanisms involved in genetic variants [1, 2]. Genistein is an …

Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement

V Aggarwal, HS Tuli, M Tania, S Srivastava… - Seminars in cancer …, 2022 - Elsevier
effects of EGCG are presented and analyzed with a special emphasis on the molecular
mechanisms of action… structural basis for the further development of novel cancer therapeutics. …

Anti‐invasive effect and pharmacological mechanism of genistein against colorectal cancer

X Chen, Y Wu, J Gu, P Liang, M Shen, J Xi, J Qin - Biofactors, 2020 - Wiley Online Library
… show anti-CRC action using genistein were mechanistically … , molecular mechanism of
genistein inhibiting colonic cancer … , assessment of antimetastatic effect of genistein for managing …

Genistein: its role in breast cancer growth and metastasis

V Mukund - Current drug metabolism, 2020 - ingentaconnect.com
… Conclusion: Genistein induces cell cycle arrest, anti-metastatic properties and … cancer cell
growth by multiple mechanisms. Genistein-mediated anti-proliferative or anti-growth effects are …

Molecular changes underlying genistein treatment of wound healing: a review

M Čoma, V Lachová, P Mitrengová, P Gál - Current Issues in Molecular …, 2021 - mdpi.com
… mediator of estrogen action in the skin [25,26]. Pharmacological effects of genistein are
mediated … Apart from genomic estrogen signaling, several non-ER effects of genistein have been …