Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
… may be characterized by the multi-omics technologies. … studies describing transcriptomics
in different tissues and its relationship with aging, in this review, we will solely focus on studies

Multi-omics approaches to human biological age estimation

I Solovev, M Shaposhnikov, A Moskalev - Mechanisms of Ageing and …, 2020 - Elsevier
… based on data obtained using most omics technologies. … human aging is based on the
utilization of deep neural networks which may be trained on any type of appropriate (usually omics

Measuring biological age using omics data

J Rutledge, H Oh, T Wyss-Coray - Nature Reviews Genetics, 2022 - nature.com
ageing clocks built using omics data. Along the way, we attempt to clarify what ageing clocks
can actually measure, how to improve ageing … of ageing enabled by omics technologies. …

Aging Atlas: a multi-omics database for aging biology

Nucleic acids research, 2021 - academic.oup.com
aging database that provides access to large gene expression and regulation datasets
created by a variety of high-throughput omics technologies … of human aging at the protein level. …

[HTML][HTML] Integrated multi-omics for novel aging biomarkers and antiaging targets

L Wu, X Xie, T Liang, J Ma, L Yang, J Yang, L Li, Y Xi… - Biomolecules, 2021 - mdpi.com
… on multi-omics technologies for aging biomarkers and novel antiaging targets. This multi-…
most complex methods for identifying human aging biomarkers. They can utilize any type of …

Aging biomarkers: from functional tests to multi‐omics approaches

KS Kudryashova, K Burka, AY Kulaga… - …, 2020 - Wiley Online Library
… been made to establish biomarkers to quantify human aging at the cellular, tissue, … to human
aging with an emphasis on biomarkers that take into account different mechanisms of aging

Single-cell omics in ageing: a young and growing field

X He, S Memczak, J Qu, JCI Belmonte, GH Liu - Nature Metabolism, 2020 - nature.com
… The study of ageing by single-cell omics technologies is only in its infancy. A multidimensional
and systematic single-cell atlas of human ageing that includes multiple organs, various …

Omics biomarkers for frailty in older adults

Y Pan, T Ji, Y Li, L Ma - Clinica Chimica Acta, 2020 - Elsevier
… frailty-related biomarkers with human aging data to identify … In addition to the omics
technologies mentioned above, other … to the study of frailty, and the progress in the research on …

The metabolomics of human aging: Advances, challenges, and opportunities

DJ Panyard, B Yu, MP Snyder - Science Advances, 2022 - science.org
… is the largest risk factor for mortality and one of the most important risk factors for chronic
diseases, understanding the omics of aging processes will be crucial. As reviewed above, …

[HTML][HTML] Connecting aging biology and inflammation in the omics era

KA Walker, N Basisty, DM Wilson… - The Journal of Clinical …, 2022 - Am Soc Clin Investig
… The application of multi-omics technology and the emergence of systems immunology has
improved our understanding of inflammation and its interaction with the aging process. Many …