Utilizing AI-Enhanced Multi-Omics Integration for Predictive Modeling of Disease Susceptibility in Functional Phenotypes

Y Zhou, X Shen, Z He, H Weng… - … of Engineering Science, 2024 - centuryscipub.com
omics technologies, omics research has accelerated the development of quantitative,
high-throughput direction, through the integration of multiple omics … as longevity and aging, and …

[HTML][HTML] Foodomics in health: Advanced techniques for studying the bioactive role of foods

I Ortea - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
… This review illustrates how the use of the latest omics technologies is being applied to
investigate the effect of diets, foods or food components on health/disease status. Bioactive food …

Multi-omics approaches to define calcific aortic valve disease pathogenesis

MC Blaser, S Kraler, TF Lüscher, E Aikawa - Circulation research, 2021 - Am Heart Assoc
… , transcriptomics, proteomics, and metabolomics to the study of valvular heart disease.
We also discuss recent forays toward the omics-based characterization of valvular (patho)biology …

[HTML][HTML] Gut–brain axis and neurodegeneration: state-of-the-art of meta-omics sciences for microbiota characterization

B Tilocca, L Pieroni, A Soggiu, D Britti… - International journal of …, 2020 - mdpi.com
… As we previously described, each omics technology sheds … limits linked to technical issues,
multi-omics integration can … microbial community changes in diversity during aging [115]. The …

[HTML][HTML] Transcriptomic effects of healthspan-promoting dietary interventions: current evidence and future directions

D Wahl, TJ LaRocca - Frontiers in Nutrition, 2021 - frontiersin.org
… in humans (71) when considering the role and transcriptomic profiles of healthy aging
interventions in aging/age-… Indeed, it may be necessary to use transcriptomics and/or other omics

[HTML][HTML] ARDD 2020: from aging mechanisms to interventions

GV Mkrtchyan, K Abdelmohsen, P Andreux… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… the discovery of novel biomarkers of human aging goes along with the development of …
aging interventions. These included not only omics data but also whole-body imaging techniques

[HTML][HTML] Nutrition and rheumatoid arthritis in the 'omics' era

M Cassotta, TY Forbes-Hernandez, D Cianciosi… - Nutrients, 2021 - mdpi.com
… and most recent applications of ‘omicstechnologies in human nutrition and in RA research,
… The opportunities and challenges of novel ‘omics technologies’ in the exploration of new …

An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease

R Nativio, Y Lan, G Donahue, S Sidoli, A Berson… - Nature …, 2020 - nature.com
… Given the complexity of the aging and neurodegenerative processes, and their … -omics
analysis of brains affected with AD versus the brains of old and younger controls. These studies

Biomarker discovery studies for patient stratification using machine learning analysis of omics data: a scoping review

E Glaab, A Rauschenberger, R Banzi, C Gerardi… - BMJ open, 2021 - bmjopen.bmj.com
… A central tool in personalised medicine and the focus of this study is the machine learning
(ML) analysis of omics profiling data to derive molecular biomarker signatures for disease-…

[HTML][HTML] Single-cell omics: A new direction for functional genetic research in human diseases and animal models

S Kong, R Li, Y Tian, Y Zhang, Y Lu, Q Ou, P Gao… - Frontiers in …, 2023 - frontiersin.org
… for single-cell omics and multi-omics techniques. The quality of separation technology is
mainly … Arterial aging studies are an important topic in the study of cardiovascular disease. The …