Omics approaches to study formation and function of human placental syncytiotrophoblast

A Jaremek, MJ Jeyarajah, G Jaju Bhattad… - Frontiers in Cell and …, 2021 - frontiersin.org
… and diverse functions of human STB as well as models commonly used for its study. Then,
we will discuss how various omics technologies have provided unprecedented insights into …

Review of multi-omics data resources and integrative analysis for human brain disorders

X Dong, C Liu, M Dozmorov - Briefings in functional genomics, 2021 - academic.oup.com
… , for example, the EU Human Brain Project initially aimed to … —using the latest omics
technologies to understand the … developing human brains) and the Aging, Dementia and TBI study

Decoding and rejuvenating human ageing genomes: Lessons from mosaic chromosomal alterations

X Dai, X Guo - Ageing Research Reviews, 2021 - Elsevier
… how mCAs induce genome ageing and human ageing. … Our understanding of how human
ageing at molecular, cellular … , from embryonic development until human ageing, in which the …

Aging biomarkers and the measurement of health and risk

S Green, L Hillersdal - History and Philosophy of the Life Sciences, 2021 - Springer
… for aging biomarkers has recently intensified with the emergence of omics fields, precision
medicine, and personalized nutrition, thus opening the possibility of measuring aging more …

Utilizing AI-Enhanced Multi-Omics Integration for Predictive Modeling of Disease Susceptibility in Functional Phenotypes

Y Zhou, X Shen, Z He, H Weng… - … of Engineering Science, 2024 - centuryscipub.com
omics technologies, omics research has accelerated the development of quantitative,
high-throughput direction, through the integration of multiple omics … as longevity and aging, and …

An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease

R Nativio, Y Lan, G Donahue, S Sidoli, A Berson… - Nature …, 2020 - nature.com
… Given the complexity of the aging and neurodegenerative processes, and their … -omics
analysis of brains affected with AD versus the brains of old and younger controls. These studies

Nano-omics: nanotechnology-based multidimensional harvesting of the blood-circulating cancerome

L Gardner, K Kostarelos, P Mallick, C Dive… - Nature Reviews …, 2022 - nature.com
… The subsequent DETECT-A study, which was the first-ever … (aged 65–75 years) without
known cancer at enrolment 17 . A total of 96 cancer diagnoses were made during the study, of …

Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging

A Li, Z Koch, T Ideker - Journal of internal medicine, 2022 - Wiley Online Library
… Therefore, if the goal is to investigate the causes of human aging, a biological clock should
be used. Chronological clocks can be applied to areas such as forensics or identifying the …

Validation of biomarkers of aging

M Moqri, C Herzog, JR Poganik, K Ying, JN Justice… - Nature medicine, 2024 - nature.com
… In addition, we recommend the use of other complementary omics data, including
metabolomics, proteomics, transcriptomics and lipidomics, the biological interpretation of which is …

[HTML][HTML] Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications

M Tomaszewski, AP Morris, JMM Howson… - Kidney international, 2022 - Elsevier
… Our earlier studies demonstrated how genetic variants modulate the extent of renal DNA
methylation within genes of importance to kidney aging. The recent analysis of DNA methylation …