[HTML][HTML] A knowledge base of clinical trial eligibility criteria

H Liu, Y Chi, A Butler, Y Sun, C Weng - Journal of biomedical informatics, 2021 - Elsevier
collaborative databaseOpenTrials” tries to integrate all available information on all clinical
trials together via the donations of structured data, but the datasets contained in OpenTrials

Update on the clinical trial landscape: analysis of ClinicalTrials. gov registration data, 2000–2020

G Gresham, JL Meinert, AG Gresham, S Piantadosi… - Trials, 2022 - Springer
… and 2020, with 64.6% open trials in 2020. A large percentage (… important step towards trial
accountability and transparency. … As trials are collaborative and often include more than one …

Discrepancies between FDA documents and ClinicalTrials. gov for Orphan Drug-related clinical trial data

MC Choudhury, I Chakraborty… - PLOS Global Public …, 2022 - journals.plos.org
… of Commons recommended that the Health Research Authority audit all trials [46]; (iii) … ; (iv)
The OpenTrials initiative intends to host all the publicly available information on a given study, …

[HTML][HTML] The ideal repository for hosting data from clinical trials: blueprint using business process management

M Gabelica, D Sapunar, M Marušić, L Puljak - F1000Research, 2023 - f1000research.com
… An ideal repository needs to develop a sustainable collaborative … The first milestone towards
open clinical trial science was … Their OpenTrials database has been created online and is …

Democratising the design and delivery of large-scale randomised, controlled clinical trials in primary care: A personal view

CC Butler - European Journal of General Practice, 2024 - Taylor & Francis
Open trials do not allow identification of mechanism of action … , and the molnupiravir arm
closed towards the end of April 2022 … Our collaboration with the Neasden Temple, the largest …

The My Cancer Genome clinical trial data model and trial curation workflow

N Jain, KF Mittendorf, M Holt… - … American Medical …, 2020 - academic.oup.com
… curation of oncology trials in collaboration with our software … By erring towards inclusivity,
we ensure these trials will be … Screenshot of gene and disease inclusion criteria for open trials

The case for open science: rare diseases

YR Rubinstein, PN Robinson, WA Gahl, P Avillach… - … open, 2020 - academic.oup.com
clinical evaluations, research collaborations, and translational validations for RD patients.
The UDN uses many hundreds of open … adoption of FAIR principles toward a critical mass of …

[HTML][HTML] Prototypical clinical trial registry based on fast healthcare interoperability resources (FHIR): design and implementation study

C Gulden, R Blasini, A Nassirian, A Stein… - JMIR medical …, 2021 - medinform.jmir.org
… The primary goal of this study is to provide access to current information on clinical studies
OpenTrials: towards a collaborative open database of all available information on all clinical

MatchMiner: an open-source platform for cancer precision medicine

H Klein, T Mazor, E Siegel, P Trukhanov… - npj Precision …, 2022 - nature.com
… place for clinicians to view all the latest available PM trials at … all living patients to all open
arms of open trials, as well as to … for CTML via widely used collaborative standard development …

Centralised full access to clinical study data can support unbiased guideline development, continuing medical education, and patient information

N McGauran, B Wieseler - Journal of European CME, 2021 - Taylor & Francis
… conventional publicly available sources. … information on the methods and results of clinical
studies on new drugs at market entry, conventional sources provide insufficient information, …