[HTML][HTML] Adipose and muscle cell co-culture system: A novel in vitro tool to mimic the in vivo cellular environment

P Kuppusamy, D Kim, I Soundharrajan, I Hwang… - Biology, 2020 - mdpi.com
… However, obesity-related dysregulation of adipose tissue promotes lipid oversupply to …
accelerate the differentiation of IMPs. In addition, the gene expression levels of PPARγ, LPL and …

LncRNA MIR99AHG enhances adipocyte differentiation by targeting miR-29b-3p to upregulate PPARγ

L Zhang, J Ma, X Pan, M Zhang, W Huang, Y Liu… - Molecular and Cellular …, 2022 - Elsevier
… was carried out before and after differentiation to identify the target lncRNAs and miRNAs. …
on adipocyte differentiation were evaluated in vitro and in vivo. Visceral adipose tissue (VAT) …

[HTML][HTML] The role of vitamin D in adipose tissue biology: adipocyte differentiation, energy metabolism, and inflammation

CY Park, SN Han - Journal of Lipid and Atherosclerosis, 2021 - ncbi.nlm.nih.gov
… of adipose tissue in vitamin D metabolism, as well as the regulatory role of vitamin D in
adipocyte differentiation, adipose tissuePPARγ and C/EBPα are necessary for adipogenesis, as …

[HTML][HTML] Studying Brown Adipose Tissue in a Human in vitro Context

I Samuelson, A Vidal-Puig - Frontiers in endocrinology, 2020 - frontiersin.org
… types including adipocytes, and can be isolated from several tissues such as … adipose-derived
stem (hMADS) cells) could be differentiated to BA-like cells when stimulated with a PPARγ

Isoform-specific functions of PPARγ in gene regulation and metabolism

W Hu, C Jiang, M Kim, Y Xiao, HJ Richter… - Genes & …, 2022 - genesdev.cshlp.org
… of PPARγ in adipocytes suggests that adipose tissue is the … numerous isoform-specific
PPARγ genomic binding sites in … a different set of genes in adipose tissue depots. In brown …

[HTML][HTML] Induction of adipose tissue browning as a strategy to combat obesity

A Kuryłowicz, M Puzianowska-Kuźnicka - International journal of …, 2020 - mdpi.com
adipocytes exist; the classical or constitutive BAT that arises during embryogenesis, and the
beige adipose tissue … of PPARγ binding activity may determine differentiation towards brown …

[HTML][HTML] Palmitoylethanolamide promotes white-to-beige conversion and metabolic reprogramming of adipocytes: contribution of PPAR

C Annunziata, C Pirozzi, A Lama, M Senzacqua… - Pharmaceutics, 2022 - mdpi.com
… to affect adipose tissue structure and function using PEA, as a PPAR-α ligand in a murine
model of obesity induced by HFD and in vitro adipocytes model. Brown adipocytes are …

PPAR control of metabolism and cardiovascular functions

D Montaigne, L Butruille, B Staels - Nature Reviews Cardiology, 2021 - nature.com
… decreased adipose tissue inflammation by derepressing PPARγ activity in mice 51 . PPARγ
also … to control adipocyte DNA methylation, target-gene transcription and insulin sensitivity in …

PPARγ acetylation orchestrates adipose plasticity and metabolic rhythms

Y He, A B'nai Taub, L Yu, Y Yao, R Zhang… - Advanced …, 2023 - Wiley Online Library
… function, and the sensitive nature and importance of PTMs, we hypothesized that the acetylation
of PPARγ is dynamically regulated in adipose tissue to affect metabolic rhythm. To test it, …

[HTML][HTML] Dehydroabietic acid alleviates high fat diet-induced insulin resistance and hepatic steatosis through dual activation of PPAR-γ and PPAR

Z Xie, G Gao, H Wang, E Li, Y Yuan, J Xu… - Biomedicine & …, 2020 - Elsevier
… remodel adipose tissue resulting in adipocyte hypertrophy … On the other hand, such
newly differentiated adipocytes are … cytokine expression via the PPARγ/PTEN pathways [31]. …