Deoxynivalenol exposure suppresses adipogenesis by inhibiting the expression of peroxisome proliferator-activated receptor gamma 2 (PPARγ2) in 3T3-L1 cells

Y Zhao, S Tang, R Lin, T Zheng, D Li, X Chen… - International Journal of …, 2020 - mdpi.com
adipocytes, mediating growth arrest and terminal differentiation in concert with PPARγ [19]. …
PPARγ1 is expressed in multiple tissues, but PPARγ2 is mainly expressed in adipose tissue

The role of PPARs in disease

N Wagner, KD Wagner - Cells, 2020 - mdpi.com
… using patient samples from subcutaneous adipose tissues of obese individuals. SLC2A4 …
that the disequilibrium of PPARγ isoforms in the adipose tissue—especially the high PPARγ∆5/…

Running against the Wnt: How Wnt/β-catenin suppresses adipogenesis

TJJ De Winter, R Nusse - Frontiers in cell and developmental biology, 2021 - frontiersin.org
tissues, including bone marrow and adipose tissue. The … factors important in adipocyte
differentiation, as has been … C/EBPα and PPARγ, both needed for terminal differentiation. This …

[HTML][HTML] … substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes

A Schaffert, I Karkossa, E Ueberham… - Environment …, 2022 - Elsevier
Adipose tissue is recognized as an important endocrine organ that secrets a … (PPARγ) is
highly expressed in adipose tissue and is considered a key regulator of adipocyte differentiation, …

Characterization and differentiation potential of mesenchymal stem cells isolated from multiple canine adipose tissue sources

U Rashid, A Yousaf, M Yaqoob, E Saba… - BMC veterinary …, 2021 - Springer
… (P = 0.418) did not change significantly during the differentiation … , adipocytes differentiation
from OM and IPFP fat sources tended to show a higher expression of FABP4 and PPARγ. …

Senescent T Cell Induces Brown Adipose Tissue “Whitening” Via Secreting IFN-γ

XX Pan, KL Yao, YF Yang, Q Ge, R Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
… Here, we compared the difference in morphology and function of adipose tissue between
young (3-… differentiation. Activation of PPARγ is necessary for brown adipocyte differentiation of …

Novel insights into adipose tissue heterogeneity

T Wang, AK Sharma, C Wolfrum - Reviews in Endocrine and Metabolic …, 2022 - Springer
… of adipose tissue, our understanding of the biological relevance of this heterogeneity and
plasticity is fractional. Therefore, establishing atlases of adipose tissue … on adipose tissue cell …

Hypertrophied human adipocyte spheroids as in vitro model of weight gain and adipose tissue dysfunction

A Ioannidou, S Alatar, R Schipper… - The Journal of …, 2022 - Wiley Online Library
… compare their differentiated adipocytes to our HUVAS to understand if and how either system
could be further improved. Similarly, Strobel et al recently published an adipocyte spheroid …

Eicosapentaenoic and docosapentaenoic acids lessen the expression of PPARγ/Cidec affecting adipogenesis in cultured 3T3-L1 adipocytes

FF Martins, MB Aguila, CA Mandarim-de-Lacerda - Acta Histochemica, 2020 - Elsevier
… CIDEC is highly expressed in adipose tissue and involved in lipid metabolism (regulation
of lipid storage, inhibition of lipolysis and motility of lipid droplet), is a novel lipid droplet-…

PPARγ and diabetes: beyond the genome and towards personalized medicine

S Cataldi, V Costa, A Ciccodicola, M Aprile - Current Diabetes Reports, 2021 - Springer
… in human adipose tissue—have been related to impaired PPARγ activity and adipose tissue
… , we highlight the need to decipher the intricate regulation of PPARγ signaling to pave the …