Dynamic positive end-expiratory pressure strategies using time and pressure recruitment at birth reduce early expression of lung injury in preterm lambs

DG Tingay, PM Pereira-Fantini… - … of Physiology-Lung …, 2022 - journals.physiology.org
… The aim is to quickly but carefully generate uniform aeration, … resuscitation guidelines suggest
that some PEEP be used for … at birth improves outcomes in newborn preterm lambs. Am J …

Impact of neonatal noninvasive resuscitation strategies on lung mechanics, tracheal pressure, and tidal volume in preterm lambs

D Bizzotto, MJ Dahl, C Veneroni… - … of Physiology-Lung …, 2024 - journals.physiology.org
… , leading to intratracheal positive end-expiratory pressure of … that SI helps to recruit the lung
rapidly, even when delivered 393 … that rapidly 486 aerating the lung of preterm lambs at birth …

Inflating pressure and not expiratory pressure initiates lung injury at birth in preterm lambs

DG Tingay, M Fatmous, K Kenna, G Dowse… - … Journal of Respiratory …, 2023 - atsjournals.org
preterm lambs that the use of dynamic PEEP results in better … of the dynamic positive
end-expiratory pressure without tidal … ), suggests that rapidly achieving aeration in the preterm

Positive end-expiratory pressure in newborn resuscitation around term: a randomized controlled trial

K Holte, H Ersdal, J Eilevstjønn, Ø Gomo… - …, 2020 - publications.aap.org
… is recommended in international guidelines for resuscitation of preterm newborns. PEEP is
… 2 would rise faster in newborns ventilated with than without PEEP because of improved lung …

Early extubation to noninvasive respiratory support of former preterm lambs improves long-term respiratory outcomes

MJ Dahl, C Veneroni, A Lavizzari… - … of Physiology-Lung …, 2021 - journals.physiology.org
… recruitment during resuscitation because our experience is that the lung of preterm lambs
cavitates … Terminal respiratory units (TRU) have more and longer alveolar secondary septa and …

Lung aeration reduces blood pressure surges caused by umbilical cord milking in preterm lambs

DA Blank, KJ Crossley, A Thiel, KA Rodgers… - Frontiers in …, 2023 - frontiersin.org
… in near term infants not requiring resuscitation (3–11). … The rapid increase in arterial blood
pressure (∼30%) and … at 7 ml/kg with a positive end-expiratory pressure of 5 cmH 2 O, rate of …

Respiratory mechanics during initial lung aeration at birth in the preterm lamb

C Veneroni, DG Tingay, KE McCall… - … of Physiology-Lung …, 2020 - journals.physiology.org
… by respiratory support with positive end-expiratory pressure (PEEP) has been proposed as
a resuscitation … The fast increase in R 5 and associated peak in the flow signal observed …

Effect of spontaneous breathing on umbilical venous blood flow and placental transfusion during delayed cord clamping in preterm lambs

E Brouwer, AB Te Pas, GR Polglase… - Archives of Disease in …, 2020 - fn.bmj.com
… -expiratory pressures may restrict net placenta-to-infant blood … pressure ventilation (PIP of
35 cmH 2 O with a positive end … it avoids the large rapid increase in blood pressure caused by …

Cardiopulmonary resuscitation of asystolic newborn lambs prior to umbilical cord clamping; the timing of cord clamping matters!

GR Polglase, GM Schmölzer, CT Roberts… - Frontiers in …, 2020 - frontiersin.org
… Therefore, an optimal CC strategy would rapidly restore … inflation pressure of 30 cm H 2 O
and end-expiratory pressure … essential for ROSC in our lambs, it may increase the risk of poor …

Early restrictive fluid strategy impairs the diaphragm force in lambs with acute respiratory distress syndrome

MM Ijland, SA Ingelse, LM van Loon, M van Erp… - …, 2022 - pubs.asahq.org
… The application of positive end-expiratory pressure itself … a closed airway at end expiration.
Catheter inflation was … To objectively quantify slow and fast twitch fibers, the Fiji image-…