M Hassert, S Arumugam, JT Harty - Immunological reviews, 2023 - Wiley Online Library
… The use of various vaccination strategies in both mouse … Targetingvaccines to the malaria preerythrocytic stage is an … Not only would this new mouse model of DC-LM prime boost …
MN Lefebvre, LL Drewry, LL Pewe… - The Journal of …, 2021 - journals.aai.org
… We find that liver-stagemalaria-specific memory CD8 T cells primed by weight-adjusted RAS vaccination can be numerically … Prime and targetimmunizationprotectsagainstliver-stage …
KM Abuga, W Jones‐Warner… - Parasite immunology, 2021 - Wiley Online Library
… miceimmunized with radiation-attenuated sporozoites (RAS) demonstrated sterile immune protectionagainstmalaria … (CPS vaccines), which acts on blood stage but not liver-stage …
Y Fu, X Lu, F Zhu, Y Zhao, Y Ding, L Ye… - Parasite …, 2020 - Wiley Online Library
… designation and the high polymorphism of the target … CQ than in mice receiving sera from miceimmunized with WKV … developed from the liverstage, leaving the unaffected liverstage to …
Z MacMillen, K Hatzakis, A Simpson, MJ Shears… - npj Vaccines, 2024 - nature.com
… to liver-stage parasites, leading to sterile protection. … To determine if prime-and-trap vaccination can protectagainst a … to reconstitution, and secondly on direct targeting of the liver, in the …
M Shahnaij, M Iyori, H Mizukami, M Kajino… - Frontiers in …, 2021 - frontiersin.org
… /c mice to evaluate the immune responses and protective … dissected from the mice that were protectedagainst sporozoite … parasite’s liverstage in preclinical settings. AAV8 is intensely …
… The transformation of sporozoites into early liverstage were … salivary gland sporozoites challenge in immunizedmice. Our … clinical trials using vaccinestargeting clinically asymptomatic …
P Bettencourt - Frontiers in Immunology, 2020 - frontiersin.org
… done to identify liver-stageprotective antigens from P. falciparum, … This study revealed that sterile protectionagainstmalaria … liver-stage response againstmalaria antigens using mouse …