Clinical management of the alcohol withdrawal syndrome

E Day, C Daly - Addiction, 2022 - Wiley Online Library
… ‘symptom-triggered’ regimens can produce rapid symptom … A trained observer assesses
the withdrawal symptoms using a … relapse during early abstinence, include baclofen, some …

Baclofen during alcohol detoxification reduces the need for additional diazepam: a randomized placebo-controlled trial

CL Crunelle, S Jegham, N Vanderbruggen… - … and Alcoholism, 2023 - academic.oup.com
… during alcohol detoxification. Baclofen was well tolerated and may be considered for the
management of alcohol withdrawal syndrome, especially useful in situations where …

The effectiveness of non-benzodiazepine, non-barbiturate medications for alcohol withdrawal syndrome: a rapid systematic review

A Ghosh, T Mahintamani, S Choudhury… - … and Alcoholism, 2021 - academic.oup.com
… for treating moderate to severe alcohol withdrawal. The efficacy of anticonvulsants (with
NMDA antagonist or GABA agonist properties), baclofen, clonidine and some antidepressant …

Baclofen therapeutics, toxicity, and withdrawal: a narrative review

JW Romito, ER Turner, JA Rosener… - SAGE open …, 2021 - journals.sagepub.com
… required to effectively treat associated withdrawal symptoms. This narrative review provides
… Although this patient’s condition rapidly improved after restarting oral baclofen, there is a …

[PDF][PDF] Management of patients with alcohol withdrawal syndrome

MM Jan, N Majeed, S Mufti, MA Margoob - Int J Indian Psychol, 2020 - academia.edu
Rapid suppression of alcohol withdrawal syndrome by baclofen. Am J Med 2002; 112:226–9…
Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam…

[HTML][HTML] Individualized, high-dose baclofen for reduction in alcohol intake in persons with high levels of consumption

C Andrade - The Journal of Clinical Psychiatry, 2020 - psychiatrist.com
… -dose baclofen (30-300 mg/d) may be a useful second-line approach in heavy drinkers who
wish to reduce levels of alcohol intake; baclofenbaclofen in the reduction of levels of alcohol

Pharmacotherapeutic management of acute alcohol withdrawal syndrome in critically Ill patients

A Glahn, PJ Proskynitopoulos, S Bleich… - Expert Opinion on …, 2020 - Taylor & Francis
faster, occurs earlier when compared to lorazepam, which leads to a faster control of withdrawal
symptoms [… Regarding the GABA B receptor agonist Baclofen, our analysis showed no …

Novel targets explored in the treatment of alcohol withdrawal syndrome

A Gupta, H Khan, A Kaur… - CNS & Neurological …, 2021 - ingentaconnect.com
… Preclinical results indicate that baclofen suppresses alcohol-drinking addiction growth
and maintenance, relapse-like drinking, and improving, enhancing, calming, and motivating …

Alcohol withdrawal syndrome in neurocritical care unit: assessment and treatment challenges

S Farrokh, C Roels, KA Owusu, SE Nelson, AM Cook - Neurocritical care, 2021 - Springer
baclofen therapy should remain on this agent to avoid baclofen withdrawal seizures. …
in the neurocritically ill due to the ability to rapidly titrate to effect and the lack of respiratory …

Preventive effects of baclofen but not diazepam on hippocampal memory and glucocorticoid alterations after prolonged alcohol withdrawal in mice

H Nadia, M Fabienne, C Pierard, M Nicole… - Frontiers in …, 2022 - frontiersin.org
… in the dHPC regardless the withdrawal periods, showing thereby prolonged … effects of
baclofen on these impairments. Interestingly, the beneficial effects of baclofen on alcohol addiction