Genomics of hypertension: the road to precision medicine

S Padmanabhan, AF Dominiczak - Nature Reviews Cardiology, 2021 - nature.com
… history of hypertension 20 . The familial risk of hypertension is likely to be due to genetic
factors because statistical modelling showed that the risk of hypertension in grandchildren …

Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses

ST Turner, E Boerwinkle - Stroke, 2023 - Taylor & Francis
… of the genetics of blood pressure regulation, the development of hypertensive complications
and … Discovery of single gene mutations that cause hypertension or hypotension in humans …

Molecular genetic framework underlying pulmonary arterial hypertension

L Southgate, RD Machado, S Gräf… - Nature Reviews …, 2020 - nature.com
… and genetic modifying factors. In this Review, we discuss the genetic aetiology of PAH
and the factors that might influence screening and treatment strategies in the future. …

… confirmation of primary aldosteronism: a position statement and consensus of the working group on endocrine hypertension of the european society of hypertension

P Mulatero, S Monticone, J Deinum, L Amar… - … of hypertension, 2020 - journals.lww.com
… aldosteronism in the general population with hypertension [5] , some … of genetic testing and
the unequivocal benefits of an early diagnosis of a familial disorder, we suggest that genetic

Pathophysiology of hypertension: the mosaic theory and beyond

DG Harrison, TM Coffman, CS Wilcox - Circulation research, 2021 - Am Heart Assoc
… The elusive nature of primary hypertension and the precise … hypertension and in models of
experimental hypertension, … vasoconstrictor and pro-hypertensive agent isolated from renal …

[HTML][HTML] Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

V Steinthorsdottir, R McGinnis, NO Williams… - Nature …, 2020 - nature.com
… risk of essential hypertension, coronary artery disease … genetic predisposition to hypertension
is a major risk factor for preeclampsia. However, comparison with gestational hypertension

… and paraganglioma: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension

JWM Lenders, MN Kerstens, L Amar… - … of hypertension, 2020 - journals.lww.com
… Tremendous progress in biochemical testing, imaging, genetics and pathophysiological …
dealing with hypertension and more importantly affected patients. Because hypertension is a …

[HTML][HTML] The variety of genetic defects explains the phenotypic heterogeneity of Familial Hyperkalemic Hypertension

M Hureaux, S Mazurkiewicz, V Boccio… - Kidney International …, 2021 - Elsevier
Introduction Familial hyperkalemic hypertension is a rare inherited form of arterial
hypertension. Four genes are responsible for this disease, the variants of these genes cause …

The global epidemiology of hypertension

KT Mills, A Stefanescu, J He - Nature Reviews Nephrology, 2020 - nature.com
… trends in mean BP levels and hypertension prevalence, awareness, treatment and …
hypertension, strategies for hypertension control, and evidence of the financial burden of …

The gut microbiome in hypertension: recent advances and future perspectives

EG Avery, H Bartolomaeus, A Maifeld, L Marko… - Circulation …, 2021 - Am Heart Assoc
… of hypertension is known to involve a diverse range of contributing factors including genetic,
… role in the development and pathogenesis of hypertension. The gastrointestinal tract, which …