… and hard nails with very slow growth of toenails and fingernails. At least five genes are known
… The FZD gene family encodes frizzled (FZD) receptors, which act as receptors for the Wnt …

… SSPS displayed characteristic nail dystrophies (six males and … disorders, among which FZD6
(frizzled class receptor 6) and … disorders have not yet been identified, the increasing usage …

… SSPS displayed characteristic nail dystrophies (six males and … disorders, among which FZD6
(frizzled class receptor 6) and … disorders have not yet been identified, the increasing usage …

… , an X-chromosomal gene encoding the signaling protein … receptor of the Frizzled receptor
family transmits the biological … We are continuing this research that may allow an expansion of …

… In addition to increasing the insights in the pathways regulating … LDL)-related receptor (LRP)5/6
and Frizzled (FZD). This activation … dysplasias caused by mutations in genes that encode …

… The interaction between the WNT ligand and the Frizzled … After incubation with
increasing concentrations of the … cause autosomal recessive ectodermal dysplasia 9, hair/nail …

… The aim of this study was to identify the underlying cause of … surface receptors complexes
composed of frizzled (FZ) and … hair, lacrimal-duct abnormalities, nail dystrophy, dry skin, and …

… Lastly, I extend a sincere acknowledgement to myself for … of the 7 transmembranes frizzled
(Fzd) receptor and the LRP5/6 co-… responsible variant for the autosomal recessive PAP-A was …

… [20], and neural tube defects (NTDs) [21]. The discovery that heterozygous LRP6 loss-of-function
mutations can cause FTA not only expands the … More recently, recessive mutations of …

… Genes acting on limb patterning are sensitive to a gene dosage effect and are often associated
with an allelic series. We extend an allele-specific gene … plane can cause congenital limb …