[HTML][HTML] Calcium homeostasis in spermatozoa: Regulatory mechanisms and biological significance

AN Nakidkina, TI Kuzmina - … ), Supplement Series A: Membrane and Cell …, 2022 - Springer
human spermatozoa. At the same time, the biological role of such exchange consists in Ca
2… through the transporter that releases Ca 2+ to the cytosol in exchange for H + or Na + (NCX)…

[HTML][HTML] Structure and function of ion channels regulating sperm motility—an overview

K Nowicka-Bauer, M Szymczak-Cendlak - International journal of …, 2021 - mdpi.com
… Like in every cell, ion homeostasis in spermatozoa is ensured by a … of sperm motility as Ca
2+ is a common secondary … for normal function of the Na + /H + -exchanger involved in the …

Role of calcium oscillations in sperm physiology

E Mata-Martínez, C Sánchez-Cárdenas, JC Chávez… - Biosystems, 2021 - Elsevier
… involved, their regulation and the physiological purpose of these … of [Ca 2+ ] i oscillatory
pathway that govern sperm motility. … K + -dependent Na + /Ca 2+ exchanger (NCKX) in the sperm

Sperm ion channels and transporters in male fertility and infertility

H Wang, LL McGoldrick, JJ Chung - Nature Reviews Urology, 2021 - nature.com
… the delicate and dynamic regulation of Ca 2+ homeostasis in sperm motility and fertility. …
and regulatory mechanisms of Na + /K + exchange and KSper is critical to understanding …

[HTML][HTML] The role of sperm membrane potential and ion channels in regulating sperm function

FM Pinto, A Odriozola, L Candenas… - International Journal of …, 2023 - mdpi.com
Ca 2+ channels and suggest that VGSC might be involved in the regulation of the basal,
linear progressive sperm motility … Defective CFTR exchangers in human sperm alter Cl − and …

Flagellar pH homeostasis mediated by Na+/H+ exchangers regulates human sperm functions through coupling with CatSper and KSper activation

M Liang, N Ji, J Song, H Kang, X Zeng - Human Reproduction, 2024 - academic.oup.com
… activity and Ca2+ homeostasis in human sperm. (A) Representative whole-cell CatSper …
Role of the Naþ/Ca2þ exchanger in calcium homeostasis and human sperm motility regulation. …

[HTML][HTML] A review on the role of bicarbonate and proton transporters during sperm capacitation in mammals

A Delgado-Bermúdez, M Yeste, S Bonet… - International Journal of …, 2022 - mdpi.com
… essential role in regulating HCO 3 − homeostasis in sperm cells … have an essential role in
the regulation of sperm motility or in … exchanger does not participate in Ca 2+ influx towards the …

[HTML][HTML] pH Homeodynamics and Male Fertility: A Coordinated Regulation of Acid-Based Balance during Sperm Journey to Fertilization

P Dai, M Zou, Z Cai, X Zeng, X Zhang, M Liang - Biomolecules, 2024 - mdpi.com
… male reproductive pH homeostasis regulators, which further promote sperm maturation in …
sperm viability and progressive motility [106]. NHEs are a class of Na + /H + exchangers

Dissecting the signaling pathways involved in the function of sperm flagellum

L Vyklicka, PV Lishko - Current opinion in cell biology, 2020 - Elsevier
regulation of flagellar ion channels and transporters that maintain sodium, potassium, calcium,
and proton homeostasis. … in exchange for sodium and are required for sperm motility and …

[HTML][HTML] Na+/H+ Exchangers (NHEs) in Mammalian Sperm: Essential Contributors to Male Fertility

CC Gardner, PF James - International Journal of Molecular Sciences, 2023 - mdpi.com
role in the regulation of intracellular pH and motility of sperm. For … , inhibits rat sperm motility
suggesting the importance of Na + … a role in energy homeostasis in mammalian sperm which …