Childhood maltreatment, serotonin transporter gene, and risk for callous and unemotional traits: A prospective investigation

CS Widom, D Miller, X Li, D Gordon, L Brzustowicz - Psychiatry research, 2020 - Elsevier
… -HTTLPR moderates the influence of childhood maltreatment … documented cases of childhood
maltreatment in the context of … these children, our results suggest that genetic risk does not

[HTML][HTML] The effects of childhood maltreatment on non-suicidal self-injury in male adolescents: the moderating roles of the monoamine oxidase A (MAOA) gene and the …

Y Gao, Y Xiong, X Liu, H Wang - … journal of environmental research and …, 2021 - mdpi.com
… [33] implicated that the association between childhood … trauma as existing moderate-severe
maltreatment if the subscale … All continuous predictive variables were mean-centered before …

[HTML][HTML] Childhood maltreatment and DNA methylation: A systematic review

CAM Cecil, Y Zhang, T Nolte - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
… , DNAm of the NR3C1 exon 1 F promoter moderated stress … and other types of adversities
showed persistently low DNAm … Aside from the serotonin transporter, two studies examined …

Interactions of childhood maltreatment and genetic variations in adult depression: A systematic review

M Li, S Liu, C D'Arcy, T Gao, X Meng - Journal of affective disorders, 2020 - Elsevier
… With core symptoms of persistent sadness and hopelessness … on the serotonin transporter
(5-HTT) gene's effect proved its … ) Val66Met polymorphism did not moderate the association …

[HTML][HTML] Association between child maltreatment and depressive symptoms in emerging adulthood: The mediating and moderating roles of DNA methylation

M Comtois-Cabana, E Barr, N Provençal… - PLoS one, 2023 - journals.plos.org
… encodes serotonin transporters responsible for serotonin … association between maltreatment
experiences in childhood and … that DNAm of these candidate genes would also moderate (…

Stress sensitization to depression following childhood adversity: Moderation by HPA axis and serotonergic multilocus profile scores

LR Starr, CB Stroud, ZA Shaw… - Development and …, 2021 - cambridge.org
… suggests that childhood adversity (CA; eg, maltreatment, … indicates that genetic variation
moderates the effect of early … case of the serotonin transporter gene and Its implications for …

[HTML][HTML] Vitamin D moderates the interaction between 5-HTTLPR and childhood abuse in depressive disorders

S Bonk, J Hertel, HU Zacharias, J Terock, D Janowitz… - Scientific reports, 2020 - nature.com
… the serotonin transporter promotor gene polymorphism (5-… The CTQ was used for self-reporting
of childhood maltreatment, … Under chronic stress and traumatization (childhood trauma), …

Childhood maltreatment history for guiding personalized antidepressant choice in major depressive disorder: Preliminary results from a systematic review

G Perna, S Dacco, A Alciati, F Cuniberti… - … and Biological …, 2021 - Elsevier
… low affinity for the serotonin transporter may be less suitable … ), whereas it did not moderate
the rate of remission across the … male US veterans with chronic and recurrent MDD and …

Associations and interactions of the serotonin receptor genes 5-HT1A, 5-HT2A, and childhood trauma with alexithymia in two independent general-population …

J Terock, A Weihs, A Teumer, J Klinger-König… - Psychiatry …, 2021 - Elsevier
… and interaction effects of childhood maltreatment and the … trauma and serotonin transporter
genes (Klauke et al., 2011; … neglect as the presence of a moderate trauma in at least one of …

A person‐centered data analytic approach to dopaminergic polygenic moderation of child maltreatment exposure

ED Handley, J Russotti, AJ Ross… - Developmental …, 2023 - Wiley Online Library
… variation moderate the effect of child maltreatment exposure on … : the serotonin transporter
gene (5HTTLPR), the dopamine … Given that not all children exposed to maltreatment develop …