Early life stress unravels epistatic genetic associations of cortisol pathway genes with depression

SC Pereira, FB Coeli-Lacchini, DA Pereira… - Journal of psychiatric …, 2024 - Elsevier
… and their interaction with childhood trauma may be important … five subdomains were above
the “moderate to severe” cutoff … test (non-parametric data) when continuous variables and by …

Serotonin transporter gene polymorphisms and maternal overprotection regulate adult social expectations on close relationships

A Bonassi, I Cataldo, G Gabrieli, B Lepri, G Esposito - Brain Sciences, 2021 - mdpi.com
… of parental bonding during childhood interact in regulating the … were also not expected to
moderate the gene*environment … romantic breakup was linked to child maltreatment [62]. The …

[HTML][HTML] A glucocorticoid-sensitive hippocampal gene network moderates the impact of early-life adversity on mental health outcomes

DM Arcego, JP Buschdorf, N O'Toole, Z Wang… - Biological …, 2024 - Elsevier
… onset that peaks between late childhood and … that genes operate in networks and therefore
used whole WGCNA to define a gene network in the pDG that was highly sensitive to chronic

Genetics of child aggression, a systematic review

E Koyama, T Kant, A Takata, JL Kennedy… - Translational …, 2024 - nature.com
… studies are increasing, (ii) the published articles tend to be moderate … on several key genes,
including serotonin transporter, MAOA, … a significant MAOA gene by childhood maltreatment

Genetic markers of the stress generation model: A systematic review

A Bahji, E Forth, T Hargreaves, K Harkness - Psychiatry research, 2021 - Elsevier
… the promoter region of the serotonin transporter gene (5-HTTLPR… that these relations may
be significantly moderated by distal stress markers, such as a history of childhood maltreatment

… serotonin reuptake inhibitor (SSRI) and other antidepressant exposure effects on anxiety and depressive behaviors in offspring: a review of findings in humans and …

SM Hutchison, LC Mâsse, JL Pawluski… - Reproductive …, 2021 - Elsevier
but not anxiety diagnoses, in children and youth up to 14 years of age [25]. It is important to
note that these three studies were limited as they did not … three years, but did not persist to 6 …

Transcriptional Modulation of Stress-Related Genes in Association with Early Life Stress Exposure and Trauma-Focused Psychotherapy in Treatment-Resistant …

RC Silva, V Dattilo, G Perusi… - … Practice and …, 2023 - connect.springerpub.com
… of childhood maltreatment, individuals exposed to ELS have an earlier onset of depressive
symptoms and are … groups for continuous measures were analyzed using a non-parametric …

Early parent-child interactions and substance use disorder: An attachment perspective on a biopsychosocial entanglement

ML Gerra, MC Gerra, L Tadonio, P Pellegrini… - Neuroscience & …, 2021 - Elsevier
… to prevent addiction and moderate insecure attachment. … Children with ambivalent attachment,
instead, are extremely … health disorder, characterized by a chronic and relapsing nature” (…

Effect of early life stress on the epigenetic profiles in depression

M Li, X Fu, W Xie, W Guo, B Li, R Cui… - Frontiers in cell and …, 2020 - frontiersin.org
… , childhood maltreatments and MDD induced different epigenetic changes at the NR3C1
promoter. Specifically, childhood maltreatments … It was assumed that chronic unpredictable mild …

[PDF][PDF] It Still Hurts: The Association of Childhood Maltreatment and Long-term Aberrant Sensory Processing of Social Signals in the Tactile and Olfactory Domains

A Maier - 2023 - scholar.archive.org
… of potentially threatening social cues that persist into adulthood. … that cortisol reactivity
to psychosocial stress moderated the … the serotonin transporter-linked promotor region (5-HTTLPR) …