The preferences of travelers determines the utility of daily activity plans. Decision-makers can affect the preference of travelers when they force private car users to use park-and-ride (P&R) facilities as a way of decreasing traffic in city centers. The P&R system has been shown to be effective in reducing uninterrupted increases in traffic congestion, especially in city centers. Therefore, the impacts of P&R on travel behavior and the daily activity plans of both worker and shopper travelers were studied in this paper. Moreover, autonomous vehicles (AVs) are a promising technology for the coming decade. A simulation of the AV as part of a multimodal system, when the P&R system was integrated in the daily activity plans, was carried out to determine the required AV fleet size needed to fulfill a certain demand and to study the impacts of AVs on the behavior of travelers (trip time and distance). Specifically, a group of travelers, who use private cars as their transport mode, was studied, and certain modifications to their daily activity plans, including P&R facilities and changing their transport mode, were introduced. Using the MATSim open-source tool, four scenarios were simulated based on the mentioned modifications. The four scenarios included (1) a simulation of the existing transport modes of the travelers, (2) a simulation of their daily activity plans when their transport modes were changed to AVs, (3) a simulation of the travelers, when P&R facilities were included in their activity chain plans, and (4) a simulation of their daily activity plans, when both P&R and AVs were included in their activity chain plans. The result showed that using the P&R system increased overall travel time, compared with using a private car. The results also demonstrated that using AVs as a replacement for conventional cars reduced travel time. In conclusion, the impact of P&R and AVs on the travel behavior of certain travelers was evaluated in this paper.