[HTML][HTML] New understanding of the damage of SARS-CoV-2 infection outside the respiratory system

Y Zhang, X Geng, Y Tan, Q Li, C Xu, J Xu, L Hao… - Biomedicine & …, 2020 - Elsevier
… surmise that after consumption of SARS-CoV-2infected wild … comprehensive assessment
of vital organ function and provide … In addition, it is important to investigate the structural and …

Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor

Y Li, W Zhou, L Yang, R You - Pharmacological research, 2020 - Elsevier
physiological and pathological conditions, and discussed its potential implication in the
susceptibility of SARS-CoV-2 infection … further deprived by SARS-CoV-2 virus upon infection, the …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
… Although most people infected with SARS-CoV-2 develop a … (SARS-CoV-2) virion consists
of the following structural proteins… After entry, the positive-sense SARS-CoV-2 genome directly …

[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… , and therapeutic strategies in SARS-CoV-2 infection. We have … cases with over 2.1 million
being infected and has mortality with over … proteins with host proteins in different physiological

SARS-CoV-2, ACE2 expression, and systemic organ invasion

UM Ashraf, AA Abokor, JM Edwards… - Physiological …, 2021 - journals.physiology.org
structural proteins: the spike protein (S), membrane protein (M), an envelope protein (E), and
a nucleocapsid protein (N) (1). Viral infections rely upon … biology of SARS-CoV-2 infection, …

[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
… This Review provides the structural and cellular foundations … to mediate membrane fusion
upon infection of a new cell 11 . … respiratory route being dominant in SARS-CoV-2 infection, the …

SARS-CoV-2: structure, biology, and structure-based therapeutics development

MY Wang, R Zhao, LJ Gao, XF Gao… - … cellular and infection …, 2020 - frontiersin.org
… proteins (S, E, M, and N) and sixteen non-structural proteins (nsp1−16). Nsp1 … effects on
splicing, translation, and protein trafficking to inhibit host defenses. Upon SARS-CoV-2 infection, …

Structural and functional basis of SARS-CoV-2 entry by using human ACE2

Q Wang, Y Zhang, L Wu, S Niu, C Song, Z Zhang, G Lu… - Cell, 2020 - cell.com
… However, SARS-CoV and MERS-CoV infection can result in life-threatening disease and
have … , causing more than 8,000 infections and approximately 800 related deaths worldwide ( …

Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing …

I Mercurio, V Tragni, F Busto, A De Grassi… - Cellular and Molecular …, 2021 - Springer
… of emergency over the new coronavirus SARS-CoV-2 pandemic. … , according to
chemical/physical space restraints and … actors of SARS-CoV-2 infection, SARS-CoV-2 spike …

SARS-CoV-2 induced intestinal responses with a biomimetic human gut-on-chip

Y Guo, R Luo, Y Wang, P Deng, T Song, M Zhang… - Science bulletin, 2021 - Elsevier
… high-risk organ for SARS-CoV-2 infection besides the lungs. … (a) Illustration of the complex
structure of the human small … and endothelial cells after SARS-CoV-2 infection of the chip. (a…