… of adipose-derived stem cells [21]; remarkably, TAZ … expression of RUNX2, a key transcription
factor in the BMP and Wnt/β-… whether TAZ acts as a downstream transcriptional factor of the …

… differentiation while inhibiting adipogenic differentiation than the other two groups. The
nuclear localization and transcriptional activity of TAZ … main mechanical cues modulator, could …

… signaling pathways YAP and TAZ, are transcriptional co-activator … Mesenchymal stem cell
lineage fate is known to be … , the modulation of neuronal differentiation by substrate stiffness …

… how YAP/TAZ control transcription. We will focus on data concerning the modulation of the
basal transcriptional … RUNX2, which controls mesenchymal stem cells differentiation along the …

… shown to direct lineage specificity for human mesenchymal stem cells (hMSCs). hMSCs
cultured on … Here, we review the data highlighting the functions of YAP/TAZ as transcriptional co-…

… To verify modulation of Runx2-driven gene expression by Wwtr1 (TAZ), first we constructed
promoter Runx2 overexpression and transcription factor Wwtr1 overexpression plasmid (…

… The appropriate organization of chromatin structures is critical for the spatiotemporal
regulation of cell type-specific gene transcription during cell differentiation. Previous studies have …

… transcription factors and is largely involved in the modulation … mediating tumour development
would help developing TAZ-… for TAZ protein stability and also promote TAZ transcription in …

… and mesenchymal stem cells through TAZ-TEAD complex formation. … through modulation
of TAZ interaction with TEAD and other transcription factors during keratinocyte differentiation (…

… stem cells (ASCs) to differentiate in adipose tissue [7], or preserve the stemness of human
mesenchymal stem cells (… This indicated that HCC increases YAP/TAZ transcriptional activity, …