Analysis of Clinical Characteristics and Neuropeptides in Patients with Dry Eye with and without Chronic Ocular Pain after FS-LASIK

L Zhao, Y Zhou, H Duan, Y Zhang, B Ma… - Ophthalmology and …, 2024 - Springer
… the Tear Film & Ocular Surface Society (TFOS) DEWS II criteria (Ocular Surface Disease Index
[… post–FS-LASIK DED with ocular pain group reported more severe dry eye symptoms and …

A Comprehensive Study on Tear Meniscus Height Inter-Eye Differences in Aqueous Deficient Dry Eye Diagnosis

H Pena-Verdeal, J Garcia-Queiruga… - Journal of Clinical …, 2024 - mdpi.com
… this diagnostic was verified by the TFOS DEWS II criterion. In all … based on the TFOS DEWS
II Diagnostic Methodology report’s … The SD reported in the literature on the symptomatology is …

Capsazepine decreases corneal pain syndrome in severe dry eye disease

D Fakih, A Guerrero-Moreno, C Baudouin… - Journal of …, 2021 - Springer
… DED also induced overexpression of genes involved in neuropathic and inflammatory pain
… and inflammatory pain in the TG of DED animals and reduced the sensation of ocular pain, …

Diquafosol sodium reduces neuronal activity in trigeminal subnucleus caudalis in a rat model of chronic dry eye disease

A Katagiri, K Tsubota, L Mikuzuki, S Nakamura… - Neuroscience …, 2023 - Elsevier
… The changes in the Vc neurons reported here were consistent with the development of
chronic ocular pain in DED. … Tfos dews ii pathophysiology report

Clinical assessments of dry eye disease: tear film and ocular surface health

KK Nichols, M Mousavi - Dry Eye Disease, 2023 - Elsevier
… The dry eye screening diagnostic algorithm in the TFOS DEWS II Diagnostic Methodology
report utilizes this approach, simplifying dry eye screening so that everyone in an eyecare …

[HTML][HTML] Maximal tear secretion evoked by controlled stimulation of corneal sensory nerves in healthy individuals and dry eye subjects

ML Merino, J Belmonte, J Rosas, MC Acosta, J Gallar… - The Ocular Surface, 2023 - Elsevier
… We report here an increase in the volume of tear secretion provoked by CO 2 application
with iOnion™, a new ophthalmic instrument that produces controlled stimulation of sensory …

Pathways and mechanisms of ocular pain and photophobia in dry eye disease

S Patel, KD Sarantopoulos - Dry Eye Disease, 2023 - Elsevier
… of the brain explains how light sensation may lead to increased pain signals, resulting in
the … with sun glasses and avoid intense light and wind tend to report less painful symptoms. …

Corneal neuropathic pain in irritable bowel syndrome: clinical findings and in vivo corneal confocal microscopy

IÇ Uçar, F Esen, SA Turhan, H Oguz… - Graefe's Archive for …, 2021 - Springer
Purpose Ocular discomfort is a common symptom in central sensitization syndromes. The
aim of this study was to evaluate ocular surface discomfort and related corneal changes in …

New perspectives in the pathophysiology and treatment of pain in patients with dry eye disease

G Giannaccare, C Ghelardini, A Mancini… - Journal of Clinical …, 2021 - mdpi.com
… patient, ranging from a mild sensation of ocular discomfort (often reported by the patient as
a “foreign body sensation”) to an intolerable pain evoked by innocuous stimuli under normal …

[PDF][PDF] Autonomic nerve activity in dry eye with decreased tear stability

M Kaido, R Arita, Y Mitsukura, R Ishida, K Tsubota - 2022 - scholar.archive.org
pain have focused on transient receptor potential vanilloid 1 (TRPV1), which is associated
with pain sensation… the parasympathetic nervous system has been reported to be important as …