Accelerated bone loss in transgenic mice expressing constitutively active TGF-β receptor type I

P Toejing, N Sakunrangsit, P Pho-On… - International Journal of …, 2023 - mdpi.com
… resulted in the defects in joint development and a failure of … and delayed development [11].
Taken together, the effects of … of heteromeric complexes of type I and type II serine/threonine …

Post-transcriptional regulatory crosstalk between MicroRNAs and canonical TGF-β/BMP signalling cascades on osteoblast lineage: a comprehensive review

HY Loh, BP Norman, KS Lai, WH Cheng… - International Journal of …, 2023 - mdpi.com
… , skeleton morphogenesis, growth plate development, and on … (Type I) and age-related or
senile osteoporosis (Type II) [10,… BMP-2 and inactivating the BMP/TGF-β axis, presenting a …

[HTML][HTML] Dual roles of misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFβ signaling

D Yu, J Hu, Z Sheng, G Fu, Y Wang, Y Chen… - Osteoarthritis and …, 2020 - Elsevier
… in the context of joint development, homeostasis maintenance, … medium with transforming
growth factor beta (TGF-β) (2 ng/mL… of type II collagen and MINK1 in tibial cartilage from normal …

Growth factor profile in calcified cartilage from the metaphysis of a calf costochondral junction, the site of initial bone formation

A Iwan, S Moskalewski, A Hyc - Biomedical Reports, 2021 - spandidos-publications.com
… of growth factors present in the epiphyseal growth plate, and … NELL-1, which is not a member
of the TGF-β superfamily, … of cartilage, such as collagen type II, cartilage oligomeric matrix …

Chemokines and bone

A Gilchrist - Bone Regulators and Osteoporosis Therapy, 2020 - Springer
… A key development in the late 1980s related to harvesting of large numbers of osteoclast
precursors (OCPs) from BM or spleen cells, which could then be cultured in the absence of …

[HTML][HTML] Diet-Stimulated Marrow Adiposity Fails to Worsen Early, Age-Related Bone Loss

C McGrath, SE Little-Letsinger, GM Pagnotti, B Sen… - Obesity Facts, 2024 - karger.com
… The region-of-interest along the tibial metaphysis was defined as a region 1,000 µm beneath
the metaphyseal growth plate. Briefly, the interface of trabecular and cortical surfaces was …

Pentosan polysulfate sodium prevents functional decline in chikungunya infected mice by modulating growth factor signalling and lymphocyte activation

PA Rudd, EXY Lim, CJM Stapledon, R Krishnan… - PloS One, 2021 - journals.plos.org
… -infected untreated mice develop the classical rheumatic … growth factor-β superfamily (TGF-β),
fibroblast growth factor … , reduced transcript levels of HLA class II molecules and reduced …

The dinosaurian femoral head experienced a morphogenetic shift from torsion to growth along the avian stem

S Egawa, CT Griffin, PJ Bishop… - … of the Royal …, 2022 - royalsocietypublishing.org
… the growth plate. Long bone elongation, in general, is mediated by mechanical stimuli …
developed (ie after morphogenesis of the medial overhang in dinosaurs). Dotted line ‘p’, the axis

Comparative approaches in vertebrate cartilage histogenesis and regulation: insights from lampreys and hagfishes

ZD Root, C Gould, M Brewer, D Jandzik, DM Medeiros - Diversity, 2021 - mdpi.com
… ECM proteins like aggrecan and type II collagen [86], it also … of articulating joints by reducing
the friction between elements [… type II collagen throughout the skeleton later in development […

The dinosaurian femoral head experienced a morphogenetic shift from torsion to growth along the avian stem

J Hutchinson - rvc-repository.worktribe.com
… was defined as the one between the ‘distal end axis’ (see … parallel as the femoral head offset
developed (figure 3a2–4). … that regulate long bone elongation at the growth plate (eg [85–87]…