The Largest Subunit of Human TFIIIC Complex, TFIIIC220, a Lysine Acetyltransferase Targets Histone H3K18

M Basu, R Bhatt, A Sharma, R Boopathi… - The Journal of …, 2024 - academic.oup.com
… we have characterized the acetyltransferase activity of the largest and DNA-binding subunit
… overexpressed against a background of knockdown and the level of histone acetylation was

Histone acetyltransferases and stem cell identity

R He, A Dantas, K Riabowol - Cancers, 2021 - mdpi.com
… that has KAT components within [29]. TAFII250 is a KAT and also a component of the TFIID
subunit … In this review, we focus on the role of histone acetylation in the regulation of stem cell …

Lysine Acetyltransferases (KATs) in Disguise: Diseases Implications

S Srivastava, S Kumar, R Bhatt… - The Journal of …, 2023 - academic.oup.com
… , the TAFII250 subunit of general transcription factor, TFIID … The acetyltransferase activity
of TAFII250 was found to be … -CoA and histone octamer did not result in histone acetylation, …

[PDF][PDF] JB Review

S Srivastava, S Kumar, R Bhatt, R Ramachandran… - scholar.archive.org
… , the TAFII250 subunit of general transcription factor, TFIID … The acetyltransferase activity
of TAFII250 was found to be … -CoA and histone octamer did not result in histone acetylation, …

[HTML][HTML] TAF1 bromodomain inhibition as a candidate epigenetic driver of congenital heart disease

RS Leigh, MJ Välimäki, BL Kaynak… - Biochimica et Biophysica …, 2023 - Elsevier
is an integral component of the pathological response, we also assessed whether TFIID subunit
… Taf6l, Taf12, and Tada1, as well as the histone acetyltransferase domain subunit Sgf29, …

[HTML][HTML] RNA polymerase II transcription with partially assembled TFIID complexes

V Hisler, P Bardot, D Detilleux, M Stierle, EG Sanchez… - bioRxiv, 2023 - ncbi.nlm.nih.gov
… In this study we have analyzed the depletion of two different TFIID subunits; TAF7 and
TAF10 in the same cellular context. Using a CRE/LoxP conditional approach in mESCs, we …

Taf2 mediates DNA binding of Taf14

BJ Klein, JT Feigerle, J Zhang, CC Ebmeier… - Nature …, 2022 - nature.com
… 7 and the histone acetyltransferase complex NuA3 8 … TFIID at least in part through the histone
mark-binding and nucleosomal DNA-binding activities of the Taf14 subunit, which in turn is

Regulation of the RNA polymerase II pre-initiation complex by its associated coactivators

S Malik, RG Roeder - Nature Reviews Genetics, 2023 - nature.com
… (TBP) subunit of the multi-subunit TFIID was originally … synergy between the histone acetyl
transferase p300 and … histone anchors to facilitate TFIID binding 26 . In another study that …

Protein acetylation and deacetylation: An important regulatory modification in gene transcription

C Xia, Y Tao, M Li, T Che, J Qu - Experimental and …, 2020 - spandidos-publications.com
… Compared with histone acetylation, acetylation of non‑histone proteins has gradually … factor
TFIID 230/250 kDa subunit (TAFII230/250) family. This family in humans is TAFII250, and it is

SVA insertion in X-linked Dystonia Parkinsonism alters histone H3 acetylation associated with TAF1 gene

T Petrozziello, AM Dios, KA Mueller, CA Vaine… - PLoS …, 2020 - journals.plos.org
histone acetylation, given that these modifications influence gene expression. Because TAF1
protein may itself exhibit histone acetyltransferase activity, … the multi-subunit TFIID complex …