Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… Hence, after the advent of SARS-CoV-2, cytokine storm was advocated as a key
pathogenetic factor in COVID-19. Numerous studies have shown that COVID-19 patients have …

An enlightening role for cytokine storm in coronavirus infection

Z Zhao, Y Wei, C Tao - Clinical Immunology, 2021 - Elsevier
… a comprehensive overview of the mechanisms underlying cytokine storm, summarizes its …
The factors sparking the cytokine storm are heterogeneous but infection is the most frequent …

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… However, the concept of cytokine storm is not limited to complications of coronavirus disease
2019 (COVID-19) [2,3], but has been observed during diverse disease outbreaks, including …

[HTML][HTML] Hypoxemia and cytokine storm in COVID-19: clinical implications

C Machado-Curbelo, A González-Quevedo - MEDICC review, 2022 - SciELO Public Health
… hypoxemia and cytokine storms in COVID-19, although it is difficult to establish the direction
of … disease and is characterized by potentially deadly lung inflammation and the advent of …

The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19

A Attiq, LJ Yao, S Afzal, MA Khan - International immunopharmacology, 2021 - Elsevier
… recent pandemic of SARS-CoV-2 has once again reminded us of theThe term “cytokine
storm” was coined more than two decades ago to define medical conditions associated with the

Underlying vulnerabilities to the cytokine storm and adverse COVID-19 outcomes in the aging immune system

LS Nidadavolu, JD Walston - The Journals of Gerontology …, 2021 - academic.oup.com
… This article provides an overview of the underlying etiologies … the consequences of the
COVID-19-related cytokine storm, … With the advent of COVID-19 and recognition of the potential …

Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - International …, 2021 - Elsevier
… SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense single-…
the Beta-CoVs sub-family. A sophisticated hyper-inflammatory reaction named cytokine storm

Is this the beginning of the end of cytokine adsorption?

JT Kielstein, A Zarbock - Critical Care Medicine, 2022 - journals.lww.com
… Especially prior to the advent of prevention by vaccinations and pharmacologic treatment
in … Among the most frequently used interventions are aimed to reduce the cytokine storm in …

Autoinflammatory diseases and cytokine storms—imbalances of innate and adaptative immunity

A Marcuzzi, E Melloni, G Zauli, A Romani… - International Journal of …, 2021 - mdpi.com
… of the main manifestations of COVID-19 infection, and the cytokine storm and its most important
components are the targets of the pharmacological treatments used to combat COVID-19 …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… discuss the latest advances in finding the potential therapeutic targets to control cytokine
stormThe hallmark of COVID-19 disease since its advent has been pulmonary manifestation. …