… drug-resistantmalaria urgently requires the development of new antimalarial drugs with novel modes of action. … on modes of action of and mechanisms of resistance to ACT drugs. …
… mechanisms of drugaction and resistance, as well as general Plasmodium biology. Insights gleaned from such experiments will continue to prove invaluable in the exploration and …
B Hanboonkunupakarn, J Tarning… - Frontiers in …, 2022 - frontiersin.org
… While the world is aiming to eliminate malaria, artemisinin resistance … mechanismof artemisinin resistance and the potential changes needed in the treatment regimens to fight resistance…
MA Shibeshi, ZD Kifle, SA Atnafie - Infection and drug resistance, 2020 - Taylor & Francis
… effect against drug-resistantmalaria parasites, and also able to reduce the parasite burden in asymptomatic individuals who serve as reservoirs for malaria … fast-acting drugs that cause …
… drugs used for chemoprevention is perennially threatened by drugresistance. This review … and spread of drugresistantmalaria, and the impact of drugresistance on the efficacy of each …
K Carolino, EA Winzeler - Current opinion in microbiology, 2020 - Elsevier
… find compounds effective at specifically clearing malaria-causing Plasmodium parasites at any … or mode of action. Here, we review recent advances in antimalarial drug discovery efforts, …
FA Siddiqui, X Liang, L Cui - … for Parasitology: Drugs and Drug Resistance, 2021 - Elsevier
… Emergence and spread of resistance in Plasmodium falciparum to the … resistance of Southeast Asia threaten global malaria control and elimination. Artemisinin (ART) resistance (or …
… of drug-resistantmalaria and their impacts on past control efforts, a brief overview of mechanisms of resistance, methods of drugresistance surveillance, the effects of resistance on …
LE Buyon, B Elsworth, MT Duraisingh - … : Drugs and Drug Resistance, 2021 - Elsevier
… This review highlights the extent of drugresistance, the putative mechanisms of resistance … malaria, drugresistant parasite strains pose a threat towards continued progress. Resistance …