Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche

C Sarnowski, DL Cousminer, N Franceschini… - Human …, 2021 - academic.oup.com
meta-analysis of AAM with half of the women being of African ancestry, we identified a new
locus … women included in the meta-analysis of genome-wide association studies of age at …

Genome-wide association study of age at menarche in the Taiwan Biobank suggests NOL4 as a novel associated gene

MC Tsai, CH Hsu, SK Chu, MH Roy-Gagnon… - Journal of Human …, 2023 - nature.com
… model and split-half meta-analysis method to verify our findings. … genome-wide association
studies (GWASs) among women of European ancestry revealed that at least 106 genetic loci

Joint genome-wide association analyses identified 49 novel loci for age at natural menopause

L Zhang, XT Wei, JJ Niu, ZX Lin, Q Xu… - The Journal of …, 2021 - academic.oup.com
… The new loci together with previously reported loci were used … To search for additional loci,
we evaluated the meta-analysisThirty-two of these 43 loci overlap with the loci obtained from …

Joint Genome-Wide Association Study Identifies Twenty-One Novel Loci for Age at Menarche and Highlights Its Causal Association with Other Complex Diseases

GJ Feng, Q Xu, JJ Ni, SS Yang, BX Han, XT Wei… - 2021 - researchsquare.com
… study in up to 438,089 participants from 3 genome-wide association studies of … to identify
more association signals that contribute to AAM, we conduct a joint GWAS meta-analysis of …

Menarche—a journey into womanhood: age at menarche and health-related outcomes in East Asians

JS Chiou, YJ Lin, CYY Chang, WM Liang… - Human …, 2024 - academic.oup.com
… We performed an AAM genome-wide association study (GWAS) with 57 890 … Genome-wide
association studies (GWAS) have identified more than 400 genetic loci for age at menarche (…

Associations between age of menarche and genetic variation in women of African descent: genome-wide association study and polygenic score analysis

MS Bryan, T Ogundiran, O Ojengbede… - J Epidemiol …, 2022 - jech.bmj.com
… Of the three studies that were not included in the meta-analysis, two … . Genome-Wide
association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus

[HTML][HTML] Genome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women

RMG Verdiesen, YT van der Schouw, CH van Gils… - medRxiv, 2020 - ncbi.nlm.nih.gov
genome-wide association studies (GWASs) could provide … also associated with natural age
at menopause. As sample sizes … 30 to prioritize the most likely causal genes at associated loci

Mendelian randomization study and metaanalysis exploring the causality of age at menarche and the risk of intracerebral hemorrhage and ischemic stroke

X Zou, L Wang, S Wang, L Zhang - CNS Neuroscience & …, 2023 - Wiley Online Library
Genome-wide association analysis (GWAS) of AAM … Conversely, a meta-analysis of 75
studies found that women with … and 7,890,254 single-nucleotide loci were analyzed (Table 1). …

[HTML][HTML] Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study

MC Magnus, AL Guyatt, RB Lawn, AB Wyss… - BMC medicine, 2020 - Springer
… , hypothesis-free genome-wide association studies, in … genome-wide association study
(GWAS) of age at menarche … (equivalent to random-effects meta-analysis). We used one-sample …

Progress in genome-wide association studies of age at natural menopause

C Xu, X Ruan, AO Mueck - Reproductive BioMedicine Online, 2023 - Elsevier
… For those aged 30–39 years old, it was 76/100,000 person-… The GWAS of ANM identified
new loci by comparing SNP in a … meta-analysis of age at menarche and natural menopause, …