Integrated bioinformatics analysis reveals novel key biomarkers in diabetic nephropathy

H Joshi, B Vastrad, N Joshi… - SAGE Open Medicine, 2022 - journals.sagepub.com
… ) curve analysis of the hub genes was carried out using pROC. The aim of this investigation
was to identify key genes and pathways and to explore potential candidate biomarkers for …

… gene expression with weighted gene correlation network analysis identifies genes whose expression is remodeled throughout physiological aging in mouse tissues

M Ferreira, S Francisco, AR Soares, A Nobre… - bioRxiv, 2021 - biorxiv.org
genes, we performed weighted gene correlation network analysis (WGCNA) to explore the
co-expression … , with each tissue’s co-expression network comprising a variable number of …

Co-Expression Network Analysis Unveiled lncRNA-mRNA Links Correlated to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance and/or …

V Fustaino, G Papoff, F Ruberti, G Ruberti - International Journal of …, 2024 - mdpi.com
weighted gene coexpression network analysis (WGCNA) to correlate the expression levels of
mRNAs and lncRNAs. Functional enrichment analysis … enrichment analysis identified about …

Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model

B Shashikadze, L Valla, SD Lombardo, C Prehn… - Molecular …, 2023 - Elsevier
… properties, these relationships can be driven even by a very small pool of genes. To
address this, we decided to pursue our analyses by using network proximity and identified a …

Identifying OGN as a Biomarker Covering Multiple Pathogenic Pathways for Diagnosing Heart Failure: From Machine Learning to Mechanism Interpretation

Y Zhu, B Chen, Y Zu - Biomolecules, 2024 - mdpi.com
… To understand the gene expression network in HF, we performed WGCNA to establish a
weighted gene co-expression network based on the expression profiles of the identified 926 …

Learning and memory impairment and transcriptomic profile in hippocampus of offspring after maternal fructose exposure during gestation and lactation

Y Zou, Q Guo, Y Chang, L Jia, L Zhai, Y Bai… - Food and Chemical …, 2022 - Elsevier
… of Genes and Genomes enriched pathway analyses identified several terms and … Weighted
gene co-expression network analysis and Gene set enrichment analysis (GSEA) of all genes

Network analysis of atherosclerotic genes elucidates druggable targets

SK Banik, S Baishya, A Das Talukdar… - BMC medical …, 2022 - Springer
… Thus, in our study we employed a branch of network medicine, gene network analysis as
a tool to identify the most crucial genes and the miRNAs that regulate these genes at the post …

[图书][B] Impacts of Sex, Biometals Homeostasis, and Dietary Fructose on Non-Alcoholic Fatty Liver Disease Pathogenesis

EA Morrell - 2023 - search.proquest.com
… pooling, and normalization procedure on them, an integrated network analysis was conducted
where gene co-expression modules were correlated with factors of interest. Modules of …

A novel approach based on metabolomics coupled with intestinal flora analysis and network pharmacology to explain the mechanisms of action of bekhogainsam …

X Meng, J Ma, AN Kang, SY Kang, HW Jung… - Frontiers in …, 2020 - frontiersin.org
… , and network pharmacology. In this study, male specific pathogen-free C57BL/6 mice were
… Our results showed that the administration of BHID to mice with STZ-induced DN prevented …

Identification of molecular subtypes of chronic obstructive pulmonary disease by gene expression profiling

张平安 - 2022 - researchsquare.com
… It is used to study the biomarkers of genes and proteins in human tissue or blood, and …
genes by case-control and case‐case comparisons and weighted gene coexpression analysis