… To define the time-window of the therapeutic effect of LFS, we analyzed its anti-convulsive …
and has a relatively wide time window [8, 9]. Therefore, we consider the subiculum to be an …

… wider therapeutic time window [6, 29, 30]. Recent clinical evidence further suggests that DBS
at the subiculum … stage is a crucial therapeutic time window for secondary epileptogenesis. …

… (<10 Hz) delivered to white matter tracts evokes a large, … high frequency or low frequency
stimulation applied at each … account of a tiny step of the time window (120 ms) which was used …

… epilepsies in adults is mesial temporal lobe epilepsy (MTLE) … threshold to 13 spikes in a 10
s sliding time window. Online … more complex with a wide variety of pathological features and …

… of hippocampal deep brain stimulation (DBS), contacts closest to the subiculum were associated
… of electrical stimulation of the subiculum in patients with refractory mesial temporal lobe …

… best result stimulating through the contacts in the subiculum, … Currently, the effect of ES
directed at the subiculum and the … commissure, at low-frequency stimulation. In comparison with …

… stimulation of the CA1 and low-frequency stimulation delivered … within a 3-s time window
before and after the stimulation was … SUBLF, low frequency stimulation applied to the subiculum; …

… in the MS at wide window of effective stimulation frequencies … While low-frequency stimulation
(LFS) has been proved to … be limited within a narrow time window 45, 62 and possibly …

… A frequent epilepsy type is temporal lobe epilepsy (TLE), … electrodes emerged as an alternative
therapeutic tool [32] and … We found a few very large NPY+/nNOS+ cells around stratum …

… Time window as indicated in (a). Time zero corresponds to … to engage downstream areas
(ie subiculum) to recruit distally … spike entrainment effect of low-frequency DBS could be …