An Activity‐Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO) in the Alzheimer's Disease Brain

P Wang, L Yu, J Gong, J Xiong, S Zi… - Angewandte Chemie …, 2022 - Wiley Online Library
… Peroxynitrite (ONOO − ) plays a critical role in Alzheimer's disease (AD). To reveal the
ONOO − influx in AD brains, an activatable activity‐based fluorescence probe Rd‐DPA3 was …

[HTML][HTML] Emerging roles of oxidative stress in brain aging and Alzheimer's disease

A Ionescu-Tucker, CW Cotman - Neurobiology of aging, 2021 - Elsevier
… In this study, DSBs were generated by physiological brain activity, but were further exacerbated
by the amyloid beta elevation found in this transgenic AD model (Suberbielle et al., 2013)…

Neural oscillations and brain stimulation in Alzheimer's disease

Z Jafari, BE Kolb, MH Mohajerani - Progress in neurobiology, 2020 - Elsevier
… For instance, slowing of oscillatory brain activity (ie, increased delta and theta power and
reduced alpha power and peak) in non-demented amyloid positive subjects has been shown to …

Increasing brain gamma activity improves episodic memory and restores cholinergic dysfunction in Alzheimer's disease

A Benussi, V Cantoni, M Grassi, L Brechet… - Annals of …, 2022 - Wiley Online Library
… ; (b) to demonstrate that γ-tACS can modulate brain activity and that the predicted enhancement
of gamma activity accounted for (or at least was associated with) the memory effects; …

What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons

C Babiloni, K Blinowska, L Bonanni, A Cichocki… - Neurobiology of …, 2020 - Elsevier
… LFPs are produced by the synchronization of activity and generation of … of brain pyramidal
neurons (Nunez, 2000). EEG/MEG activity is generated by the synchronization of activity and …

Comprehensive review on Alzheimer's disease: causes and treatment

Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
… systemic or brain diseases, (2) possible Alzheimer’s disease can … of another illness like
systemic or brain disorder, but they are … activity in the normal brain, whereas in the AD brain, its …

Role of monoamine oxidase activity in Alzheimer's disease: an insight into the therapeutic potential of inhibitors

T Behl, D Kaur, A Sehgal, S Singh, N Sharma… - Molecules, 2021 - mdpi.com
activity [127] and is in clinical trials for Alzheimer’s disease at present. Other neurodegenerative
diseases such as Huntington’s disease, … ’s disease and Alzheimer’s disease, like …

Protection against Alzheimer's disease by luteolin: Role of brain glucose regulation, anti‐inflammatory activity, and the gut microbiota‐liver‐brain axis

JW Daily, S Kang, S Park - Biofactors, 2021 - Wiley Online Library
… and progression of Alzheimer's disease (AD) by modulating brain inflammation and energy
… very low choline acetyltransferase activity in multiple regions of the brains of AD patients and …

Hyperactivity induced by soluble amyloid-β oligomers in the early stages of Alzheimer's disease

A Hector, J Brouillette - Frontiers in molecular neuroscience, 2021 - frontiersin.org
… In human, brain activity can be investigated by functional magnetic resonance imaging (fMRI),
positron emission tomography (PET), single-photon emission computed tomography (…

Hippocampus and its involvement in Alzheimer's disease: a review

YL Rao, B Ganaraja, BV Murlimanju, T Joy… - 3 Biotech, 2022 - Springer
… (NSC) functions by maintaining the brain’s microenvironment. Along with the intrinsic factors,
many extrinsic factors like dietary intake and physical activity may also influence the NSCs. …