[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… We also discuss the induction, function, downstream signaling, and existing and potential …
related signal pathways. We believe that a comprehensive understanding of CS in COVID-19

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
… Given the elicited signaling pathways, we introduced possible pathway-based therapeutic
… of several signaling pathways involved in the immunopathogenesis of COVID-19. We also …

[HTML][HTML] An aberrant STAT pathway is central to COVID-19

T Matsuyama, SP Kubli, SK Yoshinaga… - Cell Death & …, 2020 - nature.com
… JAK (Janus kinase)-STAT signaling pathways they activate. JAK family kinases (JAK1, JAK2…
signaling network (see below), could result in almost all of the clinical features of COVID-19. …

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
… Although we are now starting to understand some of the PRRs and signaling pathways in
COVID-19 pathogenesis, a number of new questions arise. These relate to all aspects of the …

[HTML][HTML] COVID-19: immunohistochemical analysis of TGF-β signaling pathways in pulmonary fibrosis

CB Vaz de Paula, S Nagashima, V Liberalesso… - International journal of …, 2021 - mdpi.com
… is observed in COVID-19. These findings … signaling pathways and pulmonary fibrosis.
The study consisted of 24 paraffin lung samples from patients who died of COVID-19 (COVID-19

Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission

DS Battagello, G Dragunas, MO Klein… - Clinical …, 2020 - portlandpress.com
… -coronavirus members. To better understand the development and transmission of COVID-19,
unveiling the signaling pathways … of cellular interaction and signaling pathways, elicited by …

Inflammatory cytokine: IL-17A signaling pathway in patients present with COVID-19 and current treatment strategy

T Shibabaw - Journal of inflammation research, 2020 - Taylor & Francis
… responsible for the immunopathology of COVID-19 and acute respiratory distress syndrome.
… IL-17A signaling and the synergic inflammatory cytokine IL-6 to manage COVID-19 patients, …

[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
… in innate and adaptive immune system in COVID-19 patients. In particular, the massive …
signaling pathways triggered by SARS-CoV-2 infection. The identification of signaling pathways

[HTML][HTML] NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients

R Kircheis, E Haasbach, D Lueftenegger… - Frontiers in …, 2020 - frontiersin.org
… lethality in COVID-19. The present perspective places a central cellular pro-inflammatory
signal pathway, NF-κB, in the context of recently published data for COVID-19 and provides a …

[HTML][HTML] … vesicle associated miRNAs regulate signaling pathways involved in COVID-19 pneumonia and the progression to severe acute respiratory corona virus-2 …

AS Meidert, S Hermann, F Brandes, B Kirchner… - Frontiers in …, 2021 - frontiersin.org
… from patients with COVID-19 pneumonia, COVID-19 ARDS, … With bioinformatically constructed
canonical pathways … differences in molecular signaling between COVID-19 and other …