Effects of dapagliflozin in patients with kidney disease, with and without heart failure

JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Heart Failure, 2021 - jacc.org
… Definite or probable ketoacidosis occurred in 2 patients without heart failure randomly
allocated to placebo; there were no cases of ketoacidosis in the dapagliflozin group. …

Estimated long-term benefit of dapagliflozin in patients with heart failure

M Vaduganathan, BL Claggett, P Jhund… - Journal of the American …, 2022 - jacc.org
… (Dapagliflozin Evaluation to Improve the Lives of Patients with Preserved Ejection Fraction
Heart Failure) … from long-term use of dapagliflozin in patients with HF with mildly reduced or …

[HTML][HTML] Effect of dapagliflozin in patients with heart failure: A systematic review and meta-analysis

AE Ali, MS Mazroua, M Elsaban, N Najam… - Global Heart, 2023 - ncbi.nlm.nih.gov
… the effect of dapagliflozin on patients with heart failure, we … mortality, and heart failure-related
hospitalization. Additionally, … and urgent heart failure visits were observed with dapagliflozin

Time to clinical benefit of dapagliflozin and significance of prior heart failure hospitalization in patients with heart failure with reduced ejection fraction

DD Berg, PS Jhund, KF Docherty, SA Murphy… - JAMA …, 2021 - jamanetwork.com
… or worsening heart failure when dapagliflozin was initiated in patients with heart failure with
… large absolute risk reductions in patients with a more recent heart failure hospitalization. …

[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

SD Solomon, JJV McMurray, B Claggett… - … England Journal of …, 2022 - Mass Medical Soc
patients with heart failure and a left ventricular ejection fraction of more than 40% to receive
dapagliflozin (… The primary outcome was a composite of worsening heart failure (which was …

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
Failure), the SGLT2 inhibitor dapagliflozin reduced the incidence of the primary composite
outcome of cardiovascular death or worsening heart failure (HF) in patients … of dapagliflozin

[HTML][HTML] The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of …
patients with HFpEF (NCT03030235), we evaluated whether the SGLT2 inhibitor dapagliflozin

Dapagliflozin for heart failure according to body mass index: the DELIVER trial

C Adamson, T Kondo, PS Jhund… - European heart …, 2022 - academic.oup.com
… Obesity is common in patients with HFpEF and is associated with higher rates of heart
failure hospitalization and worse health status. Treatment with dapagliflozin improves …

Dapagliflozin and diuretic use in patients with heart failure and reduced ejection fraction in DAPA-HF

AM Jackson, P Dewan, IS Anand, J Bělohlávek… - Circulation, 2020 - Am Heart Assoc
Failure), the sodium-glucose cotransporter 2 inhibitor dapagliflozin reduced the risk of
worsening heart failure and death in patients with heart failure and reduced ejection fraction. We …

Effects of dapagliflozin in DAPA-HF according to background heart failure therapy

KF Docherty, PS Jhund, SE Inzucchi… - European heart …, 2020 - academic.oup.com
… In the DAPA-HF trial, the SGLT2 inhibitor dapagliflozin reduced the risk of worsening
heart failure (HF) and death in patients with HF and reduced ejection fraction. We examined …