… to be identified and enabled a systematic dissection of the genetic basis of … human disease
genetics and provides an opportunity to reflect on lessons learned by the human genetics …

… Using 2,571 genome-wide significant associations, we demonstrate that the genetic …
into the disease impacts of testosterone and highlight the importance of sex-specific genetic …

… genetic variation influencing liver disease development and progression is derived from genes
… From this point of view, we focus in this perspective on how human molecular genetics of …

… human genetic disorders. We provide an updated overview of RBPs mutated in genetic
disease … illustrate underlying molecular mechanisms of disease and discuss current therapeutic …

… genetic factors may account for the predisposition of individuals to develop severe disease
… on the associations between specific human genetic variants and clinical disease severity or …

… The presence of homology in a human gene or system of study suggests potential as a
model system; however, homology alone is not sufficient justification. Environmental and life …

… animals apply to humans. Furthermore, drugs with support from human genetic studies for
… their 50s 58 found that genetic risk of Alzheimer disease was associated with mild cognitive …

… A fine-tuned interplay between microbial and human physiologies can impact multiple … with
disease 1,2 . As such, increasing evidence points to the influence of human genetic variation …

… have deep experience in areas such as disease biology, chemistry and translational
research. In contrast, the inclusion of human genetics expertise varies between companies and …

… complex human phenotypes, with potential insights for human disease onset and progression.
In this review, we summarize recent milestones in characterizing the human genetic basis …