Clinical Outcome and 7-Day Virological Clearance in High-Risk Patients with Mild–Moderate COVID-19 Treated with Molnupiravir, Nirmatrelvir/Ritonavir, or …

F Bai, T Beringheli, V Vitaletti, A Santoro, F Molà… - Infectious Diseases and …, 2024 - Springer
… , molnupiravir, and a 3-day course of remdesivir are antiviral therapies recommended in
patients with a mild-to-moderate COVID-19 … We thus investigated the effectiveness, safety, and …

Randomized trial of molnupiravir or placebo in patients hospitalized with Covid-19

JR Arribas, S Bhagani, SM Lobo, I Khaertynova… - NEJM …, 2022 - evidence.nejm.org
… The favorable safety and tolerability profile of molnupiravir … The potential of molnupiravir as
an antiviral treatment for Covid-… In this study, we report safety, efficacy, pharmacokinetic, and …

Safety and Effectiveness of Molnupiravir (LAGEVRIO®) Capsules in Japanese Patients with COVID-19: Interim Report of Post-marketing Surveillance in Japan

M Kimata, A Watanabe, Y Yanagida… - Infectious diseases and …, 2023 - Springer
… The efficacy and safety of molnupiravir were investigated in the phase III part of the global
MOVe-OUT study in outpatients with mild-to-moderate COVID-19 who were at risk for severe …

[HTML][HTML] RdRp inhibitors and COVID-19: Is molnupiravir a good option?

SMR Hashemian, MH Pourhanifeh, MR Hamblin… - Biomedicine & …, 2022 - Elsevier
safety and efficacy of molnupiravir to prevent the incidence of … for mild COVID-19 patients
treated with molnupiravir compared … efficacy of molnupiravir in Indian patients with mild COVID-…

[HTML][HTML] Effectiveness and adverse events of nirmatrelvir/ritonavir versus molnupiravir for COVID-19 in outpatient setting: multicenter prospective observational study

JJ Park, H Kim, YK Kim, SS Lee, E Jung… - Journal of Korean …, 2023 - ncbi.nlm.nih.gov
… and safety of oral treatments for COVID-19 in Korea. … /ritonavir and those treated with
molnupiravir for COVID-19. The … with molnupiravir, most of them were dysgeusia and were mild. In …

Efficacy and safety of antiviral treatments for symptomatic COVID-19 outpatients: Systematic review and network meta-analysis

M Zur, T Peselev, S Yanko, V Rotshild, I Matok - Antiviral Research, 2023 - Elsevier
… -analysis evaluated the efficacy and safety of three new antivirals (remdesivir, nirmatrelvir/ritonavir,
and molnupiravir) for treating mild to moderate COVID-19 outpatients. We included …

Comment on: Molnupiravir for the treatment of non-severe COVID-19: a systematic review and meta-analysis of 14 randomized trials with 34 570 patients

IW Chen, LC Chang, KC Hung - Journal of Antimicrobial …, 2024 - academic.oup.com
… at a higher risk of severe COVID-19 outcomes. The authors … with molnupiravir treatment,
suggesting a favourable safety … and safety of molnupiravir for treating mild-to-moderate COVID-…

Molnupiravir: A lethal mutagenic drug against rapidly mutating severe acute respiratory syndrome coronavirus 2—A narrative review

S Masyeni, M Iqhrammullah… - Journal of Medical …, 2022 - Wiley Online Library
… Clinical trials of molnupiravir as a therapy for patients with mild-to-moderate COVID-19 also
suggest … Herein, the safety concerns of molnupiravir are discussed with recent findings from …

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

SH Khoo, R Fitzgerald, T Fletcher… - Journal of …, 2021 - academic.oup.com
COVID-19 treatments. In this trial (NCT04746183) we evaluated the safety and optimal dose
of molnupiravir … Preliminary data have also been presented from a study in patients with mild

[HTML][HTML] Efficacy and safety of oral antivirals in individuals aged 80 years or older with mild-to-moderate COVID-19: preliminary report from an Italian Prescriber Center

G Bruno, S Perelli, M Giotta, N Bartolomeo… - Le Infezioni in …, 2022 - ncbi.nlm.nih.gov
… We evaluated the safety and effectiveness of oral antivirals in older people with a high
burden of co-morbidities. Randomized trials of molnupiravir and nirmatrelvir showed a lower …