New insight into neurological degeneration: Inflammatory cytokines and blood–brain barrier

J Yang, M Ran, H Li, Y Lin, K Ma, Y Yang… - Frontiers in molecular …, 2022 - frontiersin.org
neurological degeneration, we will systematically discuss the major cytokines (eg, TNFα,
IL-1β, and IL-6) that are secreted by immune cells and their impact on BBB and CNS (Figure 2). …

Exploring the etiological links behind neurodegenerative diseases: Inflammatory cytokines and bioactive kynurenines

M Tanaka, J Toldi, L Vécsei - International Journal of Molecular Sciences, 2020 - mdpi.com
… Abnormal accumulation of proteinaceous materials in and around neurons is a histopathological
hallmark in the degenerative neural tissues. Amyloid-β (Aβ) protein, tau protein, alpha-…

Neuroinflammatory markers: key indicators in the pathology of neurodegenerative diseases

A Rauf, H Badoni, T Abu-Izneid, A Olatunde… - Molecules, 2022 - mdpi.com
… Astrocytes and other neural cells communicate through … and respond by producing
inflammatory cytokines such as TNF-… in microglia blocks the degeneration of MN and prolongs the …

Interleukin-17 in chronic inflammatory neurological diseases

J Milovanovic, A Arsenijevic, B Stojanovic… - Frontiers in …, 2020 - frontiersin.org
… -inflammatory cytokine IL-10, while IL-23 has a critical role in the induction of the endogenous
cytokine … Th17-related cytokines in inflammatory and degenerative neurological diseases, …

Genetic defects and pro-inflammatory cytokines in Parkinson's disease

AF Magnusen, SL Hatton, R Rani… - Frontiers in neurology, 2021 - frontiersin.org
… -inflammatory cytokines and chemokines, which are all critical for the propagation of brain
inflammation … of pro-inflammatory cytokines and chemokines, which ultimately drive the brain …

Th17 cells and inflammation in neurological disorders: Possible mechanisms of action

Y Shi, B Wei, L Li, B Wang, M Sun - Frontiers in immunology, 2022 - frontiersin.org
… secretion of inflammatory cytokines. Under the microenvironment of pro-inflammatory cytokines
(… and their associated cytokines in promoting neuroinflammation and degeneration in AD. …

Neurodegeneration and inflammation—an interesting interplay in Parkinson's disease

C Marogianni, M Sokratous, E Dardiotis… - International journal of …, 2020 - mdpi.com
… of several cytokines implicated in dopaminergic neurons (DA) degeneration could be used
… Body Dementia patients compared to other neurological patients. Unfortunately, this method …

Plasma inflammatory cytokines are elevated in ALS

R Tortelli, C Zecca, M Piccininni… - … in neurology, 2020 - frontiersin.org
cytokines (IL-2, IL-6, IL-10, IFN-gamma, and TNF-alpha) measured in plasma has been
investigated in ALS. These biomarkers of inflammation … All the five cytokines were significantly …

Neuroinflammation: the pathogenic mechanism of neurological disorders

A Gorji - International Journal of Molecular Sciences, 2022 - mdpi.com
… mechanism that connects ischemic, degenerative, traumatic, … Moreover, modulation of
inflammatory processes and … , a pro-inflammatory cytokine that activates various cytokine

Kai‐Xin‐San Attenuates Doxorubicin‐Induced Cognitive Impairment by Reducing Inflammation, Oxidative Stress, and Neural Degeneration in 4T1 Breast Cancer Mice

W Lyu, M Ouyang, X Ma, T Han, D Pi… - Evidence‐Based …, 2021 - Wiley Online Library
… in the hippocampus, inflammatory cytokines in the serum … decreasing levels of proinflammatory
cytokines interleukin-6, … , increasing the anti-inflammatory cytokines interleukin-4 in the …