Emerging therapeutic strategies for Parkinson's disease and future prospects: A 2021 update

NA Gouda, A Elkamhawy, J Cho - Biomedicines, 2022 - mdpi.com
Parkinson’s disease (PD) is a neurodegenerative disorder pathologically distinguished by
degeneration of dopaminergic neurons in the substantia nigra pars compacta. Muscle rigidity, …

Parkinson's disease: Current drug therapy and unraveling the prospects of nanoparticles

A Paul, KS Yadav - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
… in medical history for James Parkinson's by addition of more symptoms to … Parkinson's
disease (PD) for those symptoms [4]. Being the second most familiar ND after Alzheimer's disease

Novel therapeutic interventions for combating Parkinson's disease and prospects of Nose-to-Brain drug delivery

J Ahmad, N Haider, MA Khan, S Md… - Biochemical …, 2022 - Elsevier
… Pathophysiology of Parkinson disease: Factors influencing the development of … of novel
therapeutic approaches and challenges associated with the current anti-Parkinson drug therapy

Therapeutic strategies for Parkinson's disease: promising agents in early clinical development

M Fabbri, S Perez-Lloret, O Rascol - Expert opinion on …, 2020 - Taylor & Francis
… In this review, we will focus on α- Synuclein, LRRK2, and GBA-targeted therapies, as
they offer the most promising short-term prospects and are the furthest advanced in clinical …

Cell therapy for Parkinson′ s disease is coming of age: current challenges and future prospects with a focus on immunomodulation

SD Wenker, FJ Pitossi - Gene Therapy, 2020 - nature.com
… In summary, no actual therapy prevents the progression of the disease or regenerates the
SNpc. Therefore, therapeutic strategies that prevent loss of DAn or compensate neuronal …

[HTML][HTML] Neural stem cells for Parkinson's disease management: Challenges, nanobased support, and prospects

T Oz, A Kaushik, M Kujawska - World Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
… Application of nanomaterials in stem cell therapy of Parkinson’s disease. Preoperative …
addressing the limitations of cell-based therapy for Parkinson’s disease. Moreover, “intelligent” …

Progress towards therapies for disease modification in Parkinson's disease

N Vijiaratnam, T Simuni, O Bandmann… - The Lancet …, 2021 - thelancet.com
… of Parkinson's disease pathogenesis … Parkinson's disease that are also aberrant in
sporadic cases. From this finding emerges a key concept regarding whether Parkinson's disease

[HTML][HTML] Current status and future perspectives on stem cell-based therapies for Parkinson's disease

Y Cha, TY Park, P Leblanc, KS Kim - Journal of Movement …, 2023 - ncbi.nlm.nih.gov
… In this review, we will discuss the prospects and challenges of hPSC-based cell therapy for
… Comparison of potential cell sources for cell replacement therapy for Parkinson’s disease (PD…

[HTML][HTML] New hopes for disease modification in Parkinson's Disease

W Poewe, K Seppi, K Marini, P Mahlknecht - Neuropharmacology, 2020 - Elsevier
… by the availability of multiple highly efficacious symptomatic therapies, which in their
different combinations offer a prospect of extended periods of satisfactory symptom control for a …

Mitochondrial dysfunctions in neurodegenerative diseases: Role in disease pathogenesis, strategies for analysis and therapeutic prospects

F Rey, S Ottolenghi, GV Zuccotti… - Neural Regeneration …, 2022 - journals.lww.com
… Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis,
strategies for analysis and therapeutic prospects : Neural Regeneration Research …