Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

[HTML][HTML] Nanomedicine therapies modulating macrophage dysfunction: a potential strategy to attenuate cytokine storms in severe infections

J Liu, M Wan, CJ Lyon, TY Hu - Theranostics, 2020 - ncbi.nlm.nih.gov
… These studies suggest the potential utility of macrophage depletion by liposomes, or other …
potential to induce a cytokine storm and its associated pathological effects. To the best of our …

[HTML][HTML] Cytokine storm in COVID-19 and the treatment simulacrum

A Karimi, SMR Hashemian - Biomedical and Biotechnology …, 2020 - journals.lww.com
… of molecular and cellular pathways of cytokine storms and also discuss some … cytokine storm
theory, it is rationale to evaluate immunomodulatory therapies in addition to antiviral therapy

Potential therapeutic approaches for targeted inhibition of inflammatory cytokines following COVID-19 infection-induced cytokine storm

N Morgulchik, F Athanasopoulou, E Chu… - Interface …, 2021 - royalsocietypublishing.org
… pro-inflammatory cytokines in a specific manner can result in a potentstorm, and this review
will summarize and discuss advances in targeted therapies against cytokine storms induced

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… an antiviral role, but a strong cytokine storm due to an unbalanced … to effectively suppress
cytokine storm is essential for … of IL-6 and has a therapeutic effect on cytokine storm caused

[HTML][HTML] Can natural polyphenols help in reducing cytokine storm in COVID-19 patients?

G Giovinazzo, C Gerardi, C Uberti-Foppa, L Lopalco - Molecules, 2020 - mdpi.com
… Alterations in the inflammatory cytokines pathway represent a strong signature during
SARS-… supporting their role as therapeutic tools in different acute and chronic disorders [35,41,42]. …

[HTML][HTML] Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)

C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
… and also tried to find out the best possible way to manage the … caused by cytokine storm with
existing approved therapies, to … The early results from this study seem to show that its utility

[HTML][HTML] Exploring the utility of extracellular vesicles in ameliorating viral infection-associated inflammation, cytokine storm and tissue damage

N Pillalamarri, G Ren, L Khan, A Ullah, S Jonnakuti… - Translational …, 2021 - Elsevier
… A-NP) could induce cytotoxic T cell response potent enough to kill … induced activation of
EVs then calm down cytokine and stimulate the tissue repair process [123]. The therapeutic utility

Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

C Pelaia, C Tinello, A Vatrella… - Therapeutic …, 2020 - journals.sagepub.com
… In other words, the massive and continuous release of proinflammatory cytokines and …
damage induced by the cytokine storm triggered by SARS-CoV-2, as well as on potential therapies

Highways to hell: Mechanism-based management of cytokine storm syndromes

SW Canna, RQ Cron - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
… Likewise, the utility of a broad term such as “cytokine storm” … are already on therapies that
block IL-1 or IL-6. Despite its … mediators such as cytokines, which if strong enough will promote …