Targeted and untargeted proteomics approaches in biomarker development
CA Sobsey, S Ibrahim, VR Richard, V Gaspar… - …, 2020 - Wiley Online Library
… to dramatically improve sample throughput without reducing proteome coverage in the
context of untargeted proteome profiling.80 PASEF was recently demonstrated to enable the …
context of untargeted proteome profiling.80 PASEF was recently demonstrated to enable the …
Comparative Proteome Analyses of Ureteropelvic Junction Obstruction and Surrounding Ureteral Tissue
… In this study, the proteome profiles of the obstructed segment and its surrounding distal and
… In characteristic asthma cases, airway smooth muscle hypertrophy and hyperplasia leads to …
… In characteristic asthma cases, airway smooth muscle hypertrophy and hyperplasia leads to …
The role of proteomics in the multiplexed analysis of gene alterations in human cancer
… protein turnover and increase the depth of proteome profiling [Citation19], demonstrating
that … However, the increased levels of PSA are also reported in benign prostatic hyperplasia (…
that … However, the increased levels of PSA are also reported in benign prostatic hyperplasia (…
Profiling of urinary extracellular vesicle protein signatures from patients with cribriform and intraductal prostate carcinoma in a cross-sectional study
R Matthiesen, A Carvalho, R Leão, R Sayyid, H Pereira… - 2024 - researchsquare.com
… non-invasive target to unveil proteomic signatures of IDC and Crib PCa patterns, allowing
the identi cation of a urinary biomarker protein signature for patients with Crib and IDC. Indeed…
the identi cation of a urinary biomarker protein signature for patients with Crib and IDC. Indeed…
Differential Proteome Profiling Analysis under Pesticide Stress by the Use of a Nano-UHPLC-MS/MS Untargeted Proteomic-Based Approach on a 3D-Developed …
… The aim of this study is to reveal changes in proteome profiles under stressful conditions
to … Furthermore, we adopted an untargeted proteomic-based approach with high-resolution …
to … Furthermore, we adopted an untargeted proteomic-based approach with high-resolution …
Proteomic sift through serum and endometrium profiles unraveled signature proteins associated with subdued fertility and dampened endometrial receptivity in women …
N Rashid, A Nigam, SK Jain, SH Naqvi, S Wajid - Cell and tissue research, 2020 - Springer
… Serum proteome profiles of PCOS with infertility and fertile control … hyperplasia in PCOS
females. Integration of this information with already existing data from different proteomic …
females. Integration of this information with already existing data from different proteomic …
DIA proteomics analysis through serum profiles reveals the significant proteins as candidate biomarkers in women with PCOS
Y Yu, P Tan, Z Zhuang, Z Wang, L Zhu, R Qiu… - BMC medical …, 2021 - Springer
… DIA proteomics analysis, we provided evidence of serum proteomic profile alterations in …
80 proteins were significantly differentially expressed between PCOS patients and controls, …
80 proteins were significantly differentially expressed between PCOS patients and controls, …
Longitudinal skin tape strip global proteomic assessment reveals normalization of epidermal development in atopic dermatitis patients treated with dupilumab
E Goleva, E Berdyshev, S Kreimer… - Journal of Allergy and …, 2023 - jacionline.org
… Skin proteomic profiles were correlated with AD clinical parameters (SCORAD, EASI)
and … Functionally, cluster 1 proteins were enriched for markers of epidermal hyperplasia—…
and … Functionally, cluster 1 proteins were enriched for markers of epidermal hyperplasia—…
Recent progress in mass spectrometry-based urinary proteomics
… profiling of urine has led to the discovery of several disease-associated biomarkers. Proteomic
… This review provides a progress update on urinary proteomics carried out over the past …
… This review provides a progress update on urinary proteomics carried out over the past …
Etodolac improves collagen induced rheumatoid arthritis in rats by inhibiting synovial inflammation, fibrosis and hyperplasia
Q Feng, W Xia, S Wang, G Dai, W Jiao, N Guo, H Li… - Molecular …, 2021 - Springer
… In conclusion, using DIA and PRM proteomics to study the mechanism of synovial proliferation
provided more clues for the anti-synovial hyperplasia therapy. ETD can not only relieve …
provided more clues for the anti-synovial hyperplasia therapy. ETD can not only relieve …