… and drivers of early kidney development 4 , that have been essential for the … kidney
development 44 . Of the identified interactions, many were related to stroma-secreted molecules …

… array of molecular components that maintain the podocyte tertiary foot processes through
dynamic regulation of the … The risk of developing other kidney diseases including hypertensive …

… development of such therapies requires an in-depth understanding of the molecular mechanisms
of kidney injury and of why kidney … to kidney injury, including apoptosis and regulated …

… Epigenetic regulation exerted fundamental and crucial … the development of not only the
mechanism of kidney fibrosis, … produce and release bioactive molecules to recruit inflammatory …

… have critical roles in kidney development, these topics are … molecule 1 (ICAM1) and
vascular adhesion molecule 1 (… these regulatory systems occur during various kidney diseases…

… In kidney development, WNT4 and WNT9B are of particular … –β-catenin signalling and its
regulation during kidney injury, as … cell adhesion molecules during proteinuric nephropathy 45 . …

… During the regeneration of Xenopus laevis kidneys, the … , a TF that promotes kidney
development 40 . Similarly, chromatin … role of new classes of regulatory molecules, such as long …

… its downstream signaling molecules such as Smad3 and … and fibrosis, which is negatively
regulated by Smad7. Therefore, … with a loss of nephrons and the development of renal fibrosis …

… the development and progression of chronic kidney disease (… of such responses are tightly
regulated. Chronic, unresolved … This class of endogenous molecules includes lipid mediators …

… Another important regulator of cellular senescence is SIRT1. … of kidney cell senescence
may improve the outcome of kidney transplantation. Indeed, p16 INK4a KO mice developed less …