Childhood adversity is associated with a host of mental and physical health problems across
the lifespan. Individuals who have experienced childhood adversity (eg, child abuse and …

There is considerable evidence that stressful early life events influence a variety of physical
health problems later in life. Childhood adversity has been linked to elevated rates of …

Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …

Exposure to adversity and stress early in development yields vulnerability to mental
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …

Childhood adversity has been repeatedly and robustly linked to physical and mental illness
across the lifespan. Yet, the biological pathways through which this occurs remain unclear …

Exposure to childhood adversity is a critical risk factor for the development of
psychopathology. A growing field of research examines how exposure to childhood …

Adverse childhood experiences (ACE) impair health and life expectancy and may result in
an epigenetic signature that drives increased morbidity primed during early stages of life …

Adversity in childhood has effects on mental and physical health, not only in childhood but
across the lifespan. A chief task of our research has been to define the pathways by which …

Background Adverse psychosocial exposures in early life, namely experiences such as child
maltreatment, caregiver stress or depression, and domestic or community violence, have …

Early-life stress is associated with increased vulnerability to physical and emotional health
problems across the lifespan. The recently developed neuroimmune network hypothesis …