Family studies suggest a genetic component to the etiology of chronic kidney disease (CKD)
and end stage renal disease (ESRD). Previously, we identified 16 loci for eGFR in genome …

A previous meta-analysis of genome-wide association data by the Cohorts for Heart and
Aging Research in Genomic Epidemiology and CKDGen consortia identified 16 loci …

Genome-wide association studies (GWASs) have identified multiple loci associated with
cross-sectional eGFR, but a systematic genetic analysis of kidney function decline over time …

The rate of decline of renal function varies significantly among individuals with CKD. To
understand better the contribution of genetics to CKD progression, we performed a genome …

Chronic kidney disease (CKD) is a significant public health problem, and recent genetic
studies have identified common CKD susceptibility variants. The CKDGen consortium …

Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-
decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci …

Rationale & Objective Chronic kidney disease (CKD) has a heritable component. We aimed
to quantify familial aggregation of CKD in the general population and assess the extent to …

Chronic kidney disease (CKD) is a growing health burden currently affecting 10–15% of
adults worldwide. Estimated glomerular filtration rate (eGFR) as a marker of kidney function …

Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic
complications. Through trans-ancestry meta-analysis of genome-wide association studies of …

Chronic kidney disease (CKD) is common, affecting about 10% of the general population,
and causing significant morbidity and mortality. Apart from the risk conferred by traditional …