DNA damage-repair machinery participates in maintaining genomic integrity and affects
tumorigenesis. Molecular signatures based on DNA damage-repair-related genes (DRGs) …

DNA damage repair (DDR) genes are involved in developing breast cancer. Recently, a
targeted therapeutic strategy through DNA repair machinery, including PARPi, has initially …

Breast cancer, with an overall poor clinical prognosis, is one of the most heterogeneous
cancers. DNA damage repair (DDR) and epithelial–mesenchymal transition (EMT) have …

Background As one of the most common malignancies worldwide, breast cancer (BC)
exhibits high heterogeneity of molecular phenotypes. The evolving view regarding DNA …

DNA damage repair (DDR) comprises the detection and correction of alterations in the
chemical structure of DNA. The dysfunction of the DDR process has been determined to …

DNA damage repair (DDR) is critical in maintaining normal cellular function and genome
integrity and is associated with cancer risk, progression, and therapeutic response …

Background: Triple-negative breast cancer (TNBC) is a special subtype of breast cancer with
poor prognosis. DNA damage response (DDR) is one of the hallmarks of this cancer …

Background Breast cancer has a high tumor-specific death rate and poor prognosis. In this
study, we aimed to provide a basis for the prognostic risk in patients with breast cancer using …

Lack of specific biomarkers and effective drug targets constrains therapeutic research in
breast cancer (BC). In this regard, therapeutic modulation of damage-associated molecular …

In the microenvironment of breast cancer, immune cell infiltration is associated with an
improved prognosis. To identify immune-related prognostic markers and therapeutic targets …