Co-expression based cancer staging and application

X Yu, S Cao, Y Zhou, Z Yu, Y Xu - Scientific reports, 2020 - nature.com
A novel method is developed for predicting the stage of a cancer tissue based on the
consistency level between the co-expression patterns in the given sample and samples in a …

DeePathology: deep multi-task learning for inferring molecular pathology from cancer transcriptome

B Azarkhalili, A Saberi, H Chitsaz, A Sharifi-Zarchi - Scientific reports, 2019 - nature.com
Despite great advances, molecular cancer pathology is often limited to the use of a small
number of biomarkers rather than the whole transcriptome, partly due to computational …

Predicting cancer prognosis using functional genomics data sets

J Das, KM Gayvert, H Yu - Cancer informatics, 2014 - journals.sagepub.com
Elucidating the molecular basis of human cancers is an extremely complex and challenging
task. A wide variety of computational tools and experimental techniques have been used to …

Comparative analysis of co-expression networks reveals molecular changes during the cancer progression

P Khosravi, VH Gazestani, B Law, GD Bader… - World Congress on …, 2015 - Springer
Prostate cancer is a serious genetic disease known to be one of the most widespread
cancers in men, yet the molecular changes that drive its progression are not fully …

Molecular subtyping of cancer based on distinguishing co-expression modules and machine learning

P Sun, Y Wu, C Yin, H Jiang, Y Xu, H Sun - Frontiers in genetics, 2022 - frontiersin.org
Molecular subtyping of cancer is recognized as a critical and challenging step towards
individualized therapy. Most existing computational methods solve this problem via multi …

Morphological features of single cells enable accurate automated classification of cancer from non-cancer cell lines

Z Mousavikhamene, DJ Sykora, M Mrksich… - Scientific reports, 2021 - nature.com
Accurate cancer detection and diagnosis is of utmost importance for reliable drug-response
prediction. Successful cancer characterization relies on both genetic analysis and …

Computational pathology for precision diagnosis, treatment, and prognosis of cancer

J Cheng, K Huang, J Xu - Frontiers in Medicine, 2023 - frontiersin.org
Histopathology is considered the gold standard in determining the presence and nature of
tumors. Technological advances in automated high-speed and high-resolution wholeslide …

Predicting cancer outcomes from histology and genomics using convolutional networks

P Mobadersany, S Yousefi, M Amgad… - Proceedings of the …, 2018 - National Acad Sciences
Cancer histology reflects underlying molecular processes and disease progression and
contains rich phenotypic information that is predictive of patient outcomes. In this study, we …

Extracting stage-specific and dynamic modules through analyzing multiple networks associated with cancer progression

X Ma, W Tang, P Wang, X Guo… - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
Determining the dynamics of pathways associated with cancer progression is critical for
understanding the etiology of diseases. Advances in biological technology have facilitated …

Dense, high-resolution mapping of cells and tissues from pathology images for the interpretable prediction of molecular phenotypes in cancer

JA Diao, WF Chui, JK Wang, RN Mitchell, SK Rao… - bioRxiv, 2020 - biorxiv.org
While computational methods have made substantial progress in improving the accuracy
and throughput of pathology workflows for diagnostic, prognostic, and genomic prediction …