Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …

Cancer represents a complex group of heterogeneous diseases. While many cancers share
fundamental biological processes (hallmarks of cancer) necessary for their development …

In recent years, it has become increasingly apparent that noncoding RNAs (ncRNA) are of
crucial importance for human cancer. The functional relevance of ncRNAs is particularly …

Background. Non-coding RNAs (ncRNAs) are key regulatory molecules in cellular
processes, and are potential biomarkers in many diseases. Currently, microRNAs and long …

The majority of the human genome encodes RNAs that do not code for proteins. These non-
coding RNAs (ncRNAs) affect normal expression of the genes, including oncogenes and …

MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding
RNAs that negatively regulate protein coding gene and other non-coding transcripts …

The 'classic'view of molecular oncology indicates that cancer is a genetic disease involving
tumor suppressor and oncogenic proteins. However, in the recent years, it has been …

Recent RNA sequencing studies have revealed that most of the human genome is
transcribed, but very little of the total transcriptomes has the ability to encode proteins. Long …

Protein-coding genes comprise only 3% of the human genome, while the genes that are
transcribed into RNAs but do not code for proteins occupy majority of the genome. Once …

Despite many advances in diagnosis and therapy (surgery, radiation therapy,
chemotherapy), cancer remains one of the most important public health problems …