Stopping or continuing clopidogrel 12 months after drug-eluting stent placement: the OPTIDUAL randomized trial

G Helft, PG Steg, C Le Feuvre, JL Georges… - European heart …, 2016 - academic.oup.com
Aim This open-label, randomized, and multicentre trial tested the hypothesis that, on a
background of aspirin, continuing clopidogrel would be superior to stopping clopidogrel at …

ISAR-SAFE: a randomized, double-blind, placebo-controlled trial of 6 vs. 12 months of clopidogrel therapy after drug-eluting stenting

S Schulz-Schüpke, RA Byrne, JM Ten Berg… - European heart …, 2015 - academic.oup.com
Background In patients receiving aspirin, the optimal duration of clopidogrel therapy after
drug-eluting stent (DES) implantation remains unclear. Methods This multicentre …

Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation

EL Eisenstein, KJ Anstrom, DF Kong, LK Shaw… - Jama, 2007 - jamanetwork.com
ContextRecent studies of drug-eluting intracoronary stents suggest that current antiplatelet
regimens may not be sufficient to prevent late stent thrombosis. ObjectiveTo assess the …

Clopidogrel and long-term outcomes after stent implantation for acute coronary syndrome

PM Ho, SD Fihn, L Wang, CL Bryson, E Lowy… - American heart …, 2007 - Elsevier
BACKGROUND: Little is known about the association between clopidogrel use and long-
term outcomes after stent implantation for acute coronary syndromes (ACS) in clinical …

Rationale and design of a randomized, double-blind, placebo-controlled trial of 6 versus 12 months clopidogrel therapy after implantation of a drug-eluting stent: The …

RA Byrne, S Schulz, J Mehilli, R Iijima, S Massberg… - American heart …, 2009 - Elsevier
BACKGROUND: Concern regarding the rate of delayed acute stent thrombosis associated
with drug-eluting stent (DES) treatment has resulted in upward revision of the advised …

Temporal relation between clopidogrel cessation and stent thrombosis after drug-eluting stent implantation

P Roy, L Bonello, R Torguson, T Okabe… - The American journal of …, 2009 - Elsevier
The risk of late thrombotic events and the need for prolonged dual antiplatelet therapy
detract from the clinical advantage offered by drug-eluting stents (DESs). Short-term studies …

Aspirin versus clopidogrel for long-term maintenance monotherapy after percutaneous coronary intervention: the HOST-EXAM extended study

J Kang, KW Park, H Lee, D Hwang, HM Yang… - Circulation, 2023 - Am Heart Assoc
Background: Long-term outcomes of antiplatelet monotherapy in patients who receive
percutaneous coronary intervention are unknown. The HOST-EXAM (Harmonizing Optimal …

Optimal duration of antiplatelet therapy in recipients of coronary drug-eluting stents

M Zimarino, G Renda, R De Caterina - Drugs, 2005 - Springer
Four weeks' therapy with clopidogrel, in addition to aspirin (acetylsalicylic acid), is currently
standard care after percutaneous coronary intervention (PCI) with stent implantation. The …

Stent thrombosis, clinical events, and influence of prolonged clopidogrel use after placement of drug-eluting stent: data from an observational cohort study of drug …

DW Park, SC Yun, SW Lee, YH Kim, CW Lee… - JACC: Cardiovascular …, 2008 - jacc.org
Objectives: The purpose of this study was to evaluate the risk of stent thrombosis (ST),
clinical outcomes, and the benefits of extended clopidogrel use after drug-eluting stent …

Increased risk of bleeding in patients on clopidogrel therapy after drug-eluting stents implantation: insights from the HMO Research Network-Stent Registry (HMORN …

TT Tsai, PM Ho, S Xu, JD Powers… - Circulation …, 2010 - Am Heart Assoc
Background—Studies suggest that extended clopidogrel use after drug-eluting stent (DES)
implantation may decrease the risk of myocardial infarction (MI) and death. Little is known …