Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

The origins of modern psychology are deeply rooted in the notion that stressful early-life
experiences negatively impact people's mental health. Emerging work in the field of health …

BACKGROUND: Retrospective studies show that childhood adversity is associated with
systemic inflammation in adulthood. Few prospective studies have examined whether …

Early life stressors are associated with elevated inflammation, a key physiological risk factor
for disease. However, the mechanisms by which early stress leads to inflammation remain …

Research has shown that childhood stress increases the risk of poor mental health later in
life. We examined the effect of childhood stressors on psychological distress and self …

Background No study has investigated the role of inflammation in explaining the association
between early exposures to adverse life events and depressive symptoms in adolescence …

Chronic inflammation is a potentially important pathway through which psychosocial
stressors increase risk for cardiovascular disease. However, prior research on stress and …

Stress in early life has been associated with insufficient glucocorticoid signaling in
adulthood, possibly affecting inflammation processes. Childhood maltreatment has been …

Inflammation, as a neurobiological consequence of childhood trauma, has frequently been
reported across research, however, recent investigations suggest this relationship may be …

Recent research suggests that risk for chronic diseases of aging including cardiovascular
disease, diabetes, and even cancer can be programmed early in the lifespan as a result of …