Micron-scale coherence in interphase chromatin dynamics
A Zidovska, DA Weitz… - Proceedings of the …, 2013 - National Acad Sciences
Chromatin structure and dynamics control all aspects of DNA biology yet are poorly
understood, especially at large length scales. We developed an approach, displacement …
understood, especially at large length scales. We developed an approach, displacement …
Formation of correlated chromatin domains at nanoscale dynamic resolution during transcription
Intrinsic dynamics of chromatin contribute to gene regulation. How chromatin mobility
responds to genomic processes, and whether this response relies on coordinated chromatin …
responds to genomic processes, and whether this response relies on coordinated chromatin …
Single-nucleosome imaging reveals steady-state motion of interphase chromatin in living human cells
Dynamic chromatin behavior plays a critical role in various genome functions. However, it
remains unclear how chromatin behavior changes during interphase, where the nucleus …
remains unclear how chromatin behavior changes during interphase, where the nucleus …
Chromosome dynamics in response to DNA damage
Recent advances in both the technologies used to measure chromatin movement and the
biophysical analysis used to model them have yielded a fuller understanding of chromatin …
biophysical analysis used to model them have yielded a fuller understanding of chromatin …
Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage
J Miné-Hattab, V Recamier, I Izeddin… - Molecular biology of …, 2017 - Am Soc Cell Biol
The dynamic organization of genes inside the nucleus is an important determinant for their
function. Using fast DNA tracking microscopy in Saccharomyces cerevisiae cells and …
function. Using fast DNA tracking microscopy in Saccharomyces cerevisiae cells and …
Real-time imaging of a single gene reveals transcription-initiated local confinement
Genome dynamics are intimately linked to the regulation of gene expression, the most
fundamental mechanism in biology, yet we still do not know whether the very process of …
fundamental mechanism in biology, yet we still do not know whether the very process of …
High-throughput chromatin motion tracking in living yeast reveals the flexibility of the fiber throughout the genome
H Hajjoul, J Mathon, H Ranchon, I Goiffon… - Genome …, 2013 - genome.cshlp.org
Chromosome dynamics are recognized to be intimately linked to genomic transactions, yet
the physical principles governing spatial fluctuations of chromatin are still a matter of debate …
the physical principles governing spatial fluctuations of chromatin are still a matter of debate …
[HTML][HTML] Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope
Increasing evidence points to a dynamical compartmentalization of the cell nucleus, yet the
mechanisms by which interphase chromatin moves and is positioned within nuclei remain …
mechanisms by which interphase chromatin moves and is positioned within nuclei remain …
Visualization of chromatin decompaction and break site extrusion as predicted by statistical polymer modeling of single-locus trajectories
Chromatin moves with subdiffusive and spatially constrained dynamics within the cell
nucleus. Here, we use single-locus tracking by time-lapse fluorescence microscopy to …
nucleus. Here, we use single-locus tracking by time-lapse fluorescence microscopy to …
Hi-D: nanoscale mapping of nuclear dynamics in single living cells
Bulk chromatin motion has not been analyzed at high resolution. We present Hi-D, a method
to quantitatively map dynamics of chromatin and abundant nuclear proteins for every pixel …
to quantitatively map dynamics of chromatin and abundant nuclear proteins for every pixel …