Proteomic and functional analyses of the periodic membrane skeleton in neurons
Actin, spectrin, and associated molecules form a membrane-associated periodic skeleton
(MPS) in neurons. The molecular composition and functions of the MPS remain incompletely …
(MPS) in neurons. The molecular composition and functions of the MPS remain incompletely …
The actin/spectrin membrane-associated periodic skeleton in neurons
Neurons are the most asymmetric cell types, with their axons commonly extending over
lengths that are thousand times longer than the diameter of the cell soma. Fluorescence …
lengths that are thousand times longer than the diameter of the cell soma. Fluorescence …
The role of the membrane-associated periodic skeleton in axons
AR Costa, MM Sousa - Cellular and Molecular Life Sciences, 2021 - Springer
The identification of the membrane periodic skeleton (MPS), composed of a periodic lattice
of actin rings interconnected by spectrin tetramers, was enabled by the development of …
of actin rings interconnected by spectrin tetramers, was enabled by the development of …
Prevalent presence of periodic actin–spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species
Actin, spectrin, and associated molecules form a periodic, submembrane cytoskeleton in the
axons of neurons. For a better understanding of this membrane-associated periodic skeleton …
axons of neurons. For a better understanding of this membrane-associated periodic skeleton …
The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction
AR Costa, SC Sousa, R Pinto-Costa, JC Mateus… - Elife, 2020 - elifesciences.org
Neurons have a membrane periodic skeleton (MPS) composed of actin rings interconnected
by spectrin. Here, combining chemical and genetic gain-and loss-of-function assays, we …
by spectrin. Here, combining chemical and genetic gain-and loss-of-function assays, we …
Membrane-associated periodic skeleton is a signaling platform for RTK transactivation in neurons
Actin, spectrin, and related molecules form a membrane-associated periodic skeleton (MPS)
in neurons. The function of the MPS, however, remains poorly understood. Using super …
in neurons. The function of the MPS, however, remains poorly understood. Using super …
Structural organization of the actin-spectrin–based membrane skeleton in dendrites and soma of neurons
Actin, spectrin, and associated molecules form a membrane-associated periodic skeleton
(MPS) in neurons. In the MPS, short actin filaments, capped by actin-capping proteins, form …
(MPS) in neurons. In the MPS, short actin filaments, capped by actin-capping proteins, form …
Measuring properties of the membrane periodic skeleton of the axon initial segment using 3D-structured illumination microscopy (3D-SIM)
D Micinski, L Lahti, A Abouelezz - JoVE (Journal of Visualized …, 2022 - jove.com
The axon initial segment (AIS) is the site at which action potentials initiate and constitutes a
transport filter and diffusion barrier that contribute to the maintenance of neuronal polarity by …
transport filter and diffusion barrier that contribute to the maintenance of neuronal polarity by …
Quantitative expansion microscopy for the characterization of the spectrin periodic skeleton of axons using fluorescence microscopy
Fluorescent nanoscopy approaches have been used to characterize the periodic
organization of actin, spectrin and associated proteins in neuronal axons and dendrites. This …
organization of actin, spectrin and associated proteins in neuronal axons and dendrites. This …