Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute …

SR Mehta, JF Tanguay, JW Eikelboom, SS Jolly… - The Lancet, 2010 - thelancet.com
Background Clopidogrel and aspirin are the most commonly used antiplatelet therapies for
percutaneous coronary intervention (PCI). We assessed the effect of various clopidogrel and …

Dose comparisons of clopidogrel and aspirin in acute coronary syndromes

Current–Oasis 7 Investigators - New England Journal of Medicine, 2010 - Mass Medical Soc
Background Clopidogrel and aspirin are widely used for patients with acute coronary
syndromes and those undergoing percutaneous coronary intervention (PCI). However …

Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study

SR Mehta, S Yusuf, RJG Peters, ME Bertrand… - The Lancet, 2001 - thelancet.com
Background Despite the use of aspirin, there is still a risk of ischaemic events after
percutaneous coronary intervention (PCI). We aimed to find out whether, in addition to …

Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised …

WJM Dewilde, T Oirbans, FWA Verheugt, JC Kelder… - The Lancet, 2013 - thelancet.com
Background If percutaneous coronary intervention (PCI) is required in patients taking oral
anticoagulants, antiplatelet therapy with aspirin and clopidogrel is indicated, but such triple …

Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable …

RJG Peters, SR Mehta, KAA Fox, F Zhao, BS Lewis… - Circulation, 2003 - Am Heart Assoc
Background—We studied the benefits and risks of adding clopidogrel to different doses of
aspirin in the treatment of patients with acute coronary syndrome (ACS). Methods and …

Early and late effects of clopidogrel in patients with acute coronary syndromes

S Yusuf, SR Mehta, F Zhao, BJ Gersh, PJ Commerford… - Circulation, 2003 - Am Heart Assoc
Background—The risk of ischemic events is high, both early and late after acute coronary
syndromes (ACS). We examine the benefits and risks associated with the use of adding …

Meta-analysis of the efficacy and safety of clopidogrel plus aspirin as compared to antiplatelet monotherapy for the prevention of vascular events

ADK Bowry, MA Brookhart, NK Choudhry - The American journal of …, 2008 - Elsevier
Antiplatelet agents are central to the treatment and prevention of cardiovascular disease.
Although aspirin is the most widely used agent, randomized trials have assessed whether …

Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial

SR Steinhubl, PB Berger, JT Mann III, ETA Fry… - Jama, 2002 - jamanetwork.com
ContextFollowing percutaneous coronary intervention (PCI), short-term clopidogrel therapy
in addition to aspirin leads to greater protection from thrombotic complications than aspirin …

Association of clopidogrel pretreatment with mortality, cardiovascular events, and major bleeding among patients undergoing percutaneous coronary intervention: a …

A Bellemain-Appaix, SA O'Connor, J Silvain… - Jama, 2012 - jamanetwork.com
Context Clopidogrel pretreatment is recommended for patients with acute coronary
syndromes (ACS) and stable coronary artery disease who are scheduled for percutaneous …

Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective …

BK Koo, J Kang, KW Park, TM Rhee, HM Yang… - The Lancet, 2021 - thelancet.com
Background Optimal antiplatelet monotherapy during the chronic maintenance period in
patients who undergo coronary stenting is unknown. We aimed to compare head to head the …