Abstract Poly (ADP-ribose) polymerases (PARPs or ARTDs), originally described as DNA
repair factors, have metabolic regulatory roles. PARP1, PARP2, PARP7, PARP10, and …

Abstract Poly (ADP-ribose) polymerase-1 (PARP1) is a chromatin-associated enzyme that
was described to affect chromatin compaction. Previous reports suggested a dynamic …

Abstract Poly (ADP-ribosyl) ation (PARylation) is an evolutionarily conserved reaction that
had been associated with numerous cellular processes such as DNA repair, protein …

Abstract Poly (ADP-ribose) polymerase (PARP)-2 is a nuclear enzyme that belongs to the
PARP family and PARP-2 is responsible for 5–15% of total cellular PARP activity. PARP-2 …

PPARγ-dependent gene expression during adipogenesis is facilitated by ADP-
ribosyltransferase D-type 1 (ARTD1; PARP1)-catalyzed poly-ADP-ribose (PAR) formation …

The peroxisome proliferator-activated receptor-(PPAR, NR1C3) in complex with the retinoid
X receptor (RXR) plays a central role in white adipose tissue (WAT) differentiation and …

Summary Poly (ADP-ribosyl) ation (PARylation) is a post-translational modification of
proteins mediated by PARP family members, such as PARP-1. Although PARylation has …

Poly (ADP-ribose) polymerase-2 (PARP-2) belongs to a family of enzymes that catalyze poly
(ADP-ribosyl) ation of proteins. PARP-1 and PARP-2 are so far the only PARP enzymes …

While originally described as DNA damage repair agents, recent data suggest a role for poly
(ADP-ribose) polymerase (PARP) enzymes in metabolic regulation by influencing …

Abstract Poly (ADP-ribose) polymerase-1 (PARP1) regulates gene expression as a
transcriptional cofactor and protein functions via poly (ADP-ribosyl) ation. This study was …