The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …

Aging is characterized by the functional decline of tissues and organs and increased risk of
aging-associated disorders, which pose major societal challenges and are a public health …

Advancing age is accompanied by changes in the gut microbiota characterised by a loss of
beneficial commensal microbes that is driven by intrinsic and extrinsic factors such as diet …

Changing demographics have made aging and age-related chronic diseases an enormous
and growing biomedical and societal challenge. The biological processes of aging may …

The ageing process affects the human gut microbiota phylogenetic composition and its
interaction with the immune system. Age-related gut microbiota modifications are associated …

The human gut microbiome is a collection of bacteria, protozoa, fungi, and viruses that
coexist in our bodies and are essential in protective, metabolic, and physiologic functions of …

The gut microbiota changes with age, but it is not clear to what degree these changes are
due to physiologic changes, age-associated inflammation or immunosenescence, diet …

The gut microbiota shows a wide inter-individual variation, but its within-individual variation
is relatively stable over time. A functional core microbiome, provided by abundant bacterial …

The gastrointestinal (GI) tract is a vitally important site for the adsorption of nutrients as well
as the education of immune cells. Homeostasis of the gut is maintained by the interplay of …

Our gut microbiota is a complex and dynamic ecosystem with a paramount role in shaping
our metabolic and immunological functions. Recent research suggests that aging may …