Background Alzheimer's disease is a debilitating and highly heritable neurological
condition. As such, genetic studies have sought to understand the genetic architecture of …

With the advent of genome-wide association studies (GWAS) and next-generation
sequencing, more than 20 risk loci that affect Alzheimer's disease have been identified …

In the search for new genes in Alzheimer's disease, classic linkage-based and candidate-
gene-based association studies have been supplanted by exome sequencing, genome …

As the size of genome-wide association studies increase, the number of associated trait loci
identified inevitably increase. One welcomes this if it allows the better delineation of the …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by
previous studies; however, a large portion of the genetic risk for this disease remains …

Objective Genome‐wide association studies (GWAS) have identified over 30 susceptibility
loci associated with Alzheimer's disease (AD). Using AD GWAS data from the International …

Background Alzheimer's disease (AD) is a complex multifactorial neurodegenerative
disorder and the most common form of dementia. AD is highly heritable, with heritability …

Genome-wide association studies (GWASs) have revealed a plethora of putative
susceptibility genes for Alzheimer's disease (AD). With the sole exception of the APOE gene …

Alzheimer's disease (AD) is highly heritable and recent studies have identified over 20
disease-associated genomic loci. Yet these only explain a small proportion of the genetic …

Introduction The ability to identify individuals at increased genetic risk for Alzheimer's
disease (AD) may streamline biomarker and drug trials and aid clinical and personal …