Controlling the particle structure of tumor-targeting nanomedicines in vivo remains
challenging but must be achieved to control their in vivo fate and functions. Molecular …

To achieve high precision and efficacy in disease treatment, biodegradability and
environmental responsivity are highly desired in drug delivery systems. Having a polylactide …

Polymeric nanoscale drug carrier systems are of particular interest for tumor therapy, offering
significant advantages of improved targeting and efficacy. Herein, a well-defined polymeric …

We demonstrate the conjugation of the cancer drug doxorubicin (DOX) to poly
(methacryloyloxyethyl phosphorylcholine)(polyMPC), linked by hydrazone groups, using (1) …

Drug delivery systems with targeted and smart properties have emerged as an efficient
strategy to overcome the challenges of cancer chemotherapy such as toxic side effects and …

Using the 3rd generation Grubbs' catalyst as the initiator, diblock brush polymer drug
conjugates (BPDCs) were synthesized by sequential ring-opening metathesis …

Designing an efficient nanocarrier to target multiple types of cancer remains a major
challenge in the development of cancer nanomedicines. The majority of systemically …

Synthesis of polyfluorene (PF) based theranostic amphiphilic copolymers with
simultaneously high drug loading efficiency and tumor microenvironment-specific …

To achieve a conjugated drug delivery system with high drug loading but minimal long-term
side effects, a degradable brush polymer–drug conjugate (BPDC) was synthesized through …

Internalization of drug delivery micelles into cancer cells is a crucial step for antitumor
therapeutics. Novel amphiphilic star‐shaped copolymers with zwitterionic phosphorylcholine …